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Head-to-head · Cost-Efficiency Index

CoreAge Rx vs Science & Co

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A · #1

CoreAge Rx

Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.

Visit CoreAge Rx
VS
Grade C · #62

Science & Co

A twelve-month committer, or someone who values a company stating plainly what it is and is not.

Visit Science & Co

The verdict

Winner · CoreAge RxGrade A vs C

CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 74. Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. Science & Co still earns a CA twelve-month committer, or someone who values a company stating plainly what it is and is not.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

93
76

Price Transparency

97
74

Nationwide Access

98
62

Formulation Options

84
74

Clinical Oversight

90
76

Contract Flexibility

95
84

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCoreAge RxScience & Co
Cost-Efficiency Index94/10074/100
Semaglutide / mo$99/mo$149/mo month-to-month; $79 only on a twelve-month plan
Tirzepatide / mo$149/mo$199/mo month-to-month; $125 only on a twelve-month plan
Semaglutide / yr (modeled)$1,188$1,788
Tirzepatide / yr (modeled)$1,788$2,388
CoverageAll 50 statesNot disclosed
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank here#1#62

CoreAge Rx

94/100

Where the value is

  • Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
  • Both compounded semaglutide and tirzepatide on one account at published prices
  • Available in all 50 states — no coverage gamble

The tradeoffs

  • Not the rock-bottom sticker price — 30 of the 381 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
  • No FDA-approved brand-name option (compounded only)
Visit CoreAge Rx

Full CoreAge Rx review →

Science & Co

74/100

Where the value is

  • States twice in its footer that "Science and Co, Inc. is not a 503A or 503B compounding facility"
  • Its own FAQ names the commitment behind the headline: "Plans start at $79 a month on the 12 month plan"
  • The printed saving corroborates the reference price — 79 divided by 149 is 53%, exactly the "Save 47%" shown

The tradeoffs

  • The number it leads with is a twelve-month commitment; the per-month rates are $149 and $199
  • Only two figures are published per drug, so a three- or six-month plan cannot be priced without starting an intake
Visit Science & Co

Full Science & Co review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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