Skip to content
WeighLab

Lttl vs Ryze Rx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Lttl

Affiliate partner

Shoppers who want a low price without prepaying, and who are fine with a refill that ships and bills every four weeks.

Semaglutide / month
$99 per 4 weeksCompounded, auto-refill
Tirzepatide / month
$149 per 4 weeksCompounded, auto-refill
Index 61/100 · Grade CChecked October 2026

Ryze Rx

Provider comparison

Shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.

Semaglutide / month
Not disclosedVials from $119; duration depends on dose
Tirzepatide / month
Not disclosedVials from $199; duration depends on dose
Index 63/100 · Grade CChecked October 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Ryze Rx has the higher Cost-Efficiency Index: 63/100 versus 61/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Lttl
Coverage not published
Ryze Rx
All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Lttl

Ryze Rx

Semaglutide / month
Lttl: $99 per 4 weeksCompounded, auto-refill
Ryze Rx: Not disclosedVials from $119; duration depends on dose
Tirzepatide / month
Lttl: $149 per 4 weeksCompounded, auto-refill
Ryze Rx: Not disclosedVials from $199; duration depends on dose
Semaglutide / year (modeled)
Lttl: $1,28713 charges
Ryze Rx: —
Tirzepatide / year (modeled)
Lttl: $1,93713 charges
Ryze Rx: —
State availability
Lttl: Coverage not published
Ryze Rx: All 50 states
Oral / sublingual option listed
Lttl: Yes
Ryze Rx: Yes
Brand-name access listed
Lttl: Not confirmed
Ryze Rx: Not confirmed
Provider facts checked
Lttl: October 2026
Ryze Rx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Lttl

Shoppers who want a low price without prepaying, and who are fine with a refill that ships and bills every four weeks.

Reasons to consider it

  • Every medication and supply length is priced on its plans page before checkout
  • Longer supplies trim the price only a little: semaglutide is $96, $93 or $89 per four weeks on 12-, 24- or 52-week supplies, so month to month costs you almost nothing extra
  • Named medical advisory board (pharmacist, nurse practitioner, physical therapist) rather than zero disclosure

What to weigh up

  • Billing is every four weeks, so a year is 13 charges: about $1,287 on semaglutide and $1,937 on tirzepatide
  • The struck-through $249 and $339 beside each price are not a price anyone is quoted, so ignore the "savings" figures
  • A first-month discount of up to $140 is applied automatically, so check what your second order costs

Ryze Rx

Shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.

Reasons to consider it

  • Lists injectable semaglutide and tirzepatide by vial strength, plus oral versions of both drugs
  • Physician consultation, ongoing clinical support and shipping are included
  • Licensed providers serve all 50 states

What to weigh up

  • The injectable catalog prices vials, so confirm how many weeks your prescription covers before treating a figure as a monthly cost
  • Pharmacy partners are not named
  • No detailed prescription refund policy is published

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

LttlRyze Rx
Normalized Cost/Month
Lttl:
76/100
Ryze Rx:
45/100
Price Transparency
Lttl:
78/100
Ryze Rx:
54/100
Nationwide Access
Lttl:
24/100
Ryze Rx:
86/100
Formulation Options
Lttl:
77/100
Ryze Rx:
51/100
Clinical Oversight
Lttl:
76/100
Ryze Rx:
80/100
Contract Flexibility
Lttl:
20/100
Ryze Rx:
77/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

More provider matchups
Choose a different comparison

Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.