Head-to-head · Cost-Efficiency Index
HealthHub vs Piper
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
HealthHub
Shoppers who want a choice between injectable and needle-free oral GLP-1 formats from one provider.
Visit HealthHubPiper
Shoppers who understand the pricing is billed weekly and want a flat, dose-independent recurring charge from a named pharmacy.
Visit PiperThe verdict
HealthHub takes it, leading the Cost-Efficiency Index 67 to 66. HealthHub is a LegitScript-certified telehealth platform (seal 46103909) selling compounded semaglutide and tirzepatide in FOUR formats standard injection, oral dissolving tablet, and a sublingual liquid. Piper still earns a C — Shoppers who understand the pricing is billed weekly and want a flat, dose-independent recurring charge from a named pharmacy.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs HealthHub.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | HealthHub | Piper |
|---|---|---|
| Cost-Efficiency Index | 67/100 | 66/100 |
| Semaglutide / mo | $99/mo (compounded) | $135/week ($585/mo equiv.) |
| Tirzepatide / mo | $199/mo (compounded) | $199/week ($862/mo equiv.) |
| Semaglutide / yr (modeled) | $1,188 | $7,020 |
| Tirzepatide / yr (modeled) | $2,388 | $10,344 |
| Coverage | Coverage not published | All 50 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #127 | #132 |
HealthHub
67/100Where the value is
- Genuine LegitScript certification, independently verified today (seal 46103909, live checker link)
- Four real format choices for the same two molecules — standard injection, oral dissolving tablet, and sublingual
- The injectable format is the CHEAPEST option ($99 sema / $199 tirz), not the oral tablet
The tradeoffs
- The $99/$199 injection prices are explicitly framed as covering 'your first 4 weeks' or 'your first month' — no month-2+ recurring price is published anywhere
- No compounding pharmacy is named on any page reached today
Piper
66/100Where the value is
- Names two specific 503A partner compounding pharmacies (Hallandale Pharmacy, VialsRx) rather than staying anonymous
- Nationwide all-50 access with flat pricing at every dose
- LegitScript-certified seal displayed for the current joinpolly.com domain
The tradeoffs
- The headline $135/$199 prices are billed WEEKLY, not monthly — the real monthly-equivalent cost is roughly $585 (semaglutide) and $862 (tirzepatide)
- Compounded only — no brand-name or oral route
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.