Head-to-head · Cost-Efficiency Index
Factor Health MD vs Piper
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Factor Health MD
Those willing to commit to a 12-month term to capture the lowest headline price, since flexible month-to-month is nearly double.
Visit Factor Health MDPiper
Shoppers who understand the pricing is billed weekly and want a flat, dose-independent recurring charge from a named pharmacy.
Visit PiperThe verdict
Factor Health MD takes it, leading the Cost-Efficiency Index 67 to 66. Factor Health MD is a compounded-GLP-1 and general telehealth clinic (LegitScript-certified per its footer badge, based in St. Petersburg, FL) offering semaglutide and tirzepatide. Piper still earns a C — Shoppers who understand the pricing is billed weekly and want a flat, dose-independent recurring charge from a named pharmacy.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Factor Health MD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Factor Health MD | Piper |
|---|---|---|
| Cost-Efficiency Index | 67/100 | 66/100 |
| Semaglutide / mo | $99/mo (all doses, annual plan, compounded) | $135/week ($585/mo equiv.) |
| Tirzepatide / mo | $149/mo (all doses, annual plan, compounded) | $199/week ($862/mo equiv.) |
| Semaglutide / yr (modeled) | $1,188 | $7,020 |
| Tirzepatide / yr (modeled) | $1,788 | $10,344 |
| Coverage | Coverage not published | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #125 | #132 |
Factor Health MD
67/100Where the value is
- Every plan includes ALL doses at one flat rate with no per-mg escalation, confirmed explicitly in its own FAQ
- LegitScript certified (badge displayed in the site footer)
- Genuinely no long-term contract required for the flexible monthly tier, per its own FAQ
The tradeoffs
- The widely advertised 'From $99/mo' headline (used in the site's own page title) only applies to the 12-month prepaid Annual plan — the real no-commitment month-to-month price is $189/mo for semaglutide and $289/mo for tirzepatide, 91-94% higher
- No compounding pharmacy is individually named, only a generic 'network of licensed, FDA-regulated pharmacies'
Piper
66/100Where the value is
- Names two specific 503A partner compounding pharmacies (Hallandale Pharmacy, VialsRx) rather than staying anonymous
- Nationwide all-50 access with flat pricing at every dose
- LegitScript-certified seal displayed for the current joinpolly.com domain
The tradeoffs
- The headline $135/$199 prices are billed WEEKLY, not monthly — the real monthly-equivalent cost is roughly $585 (semaglutide) and $862 (tirzepatide)
- Compounded only — no brand-name or oral route
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.