Head-to-head · Cost-Efficiency Index
CoreAge Rx vs Piper
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
CoreAge Rx
Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.
Visit CoreAge RxPiper
Nationwide shoppers who want both molecules disclosed at fair prices and will do their own diligence on the pharmacy.
Visit PiperThe verdict
CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 82. Best value on the board: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. Piper still earns a B− — Nationwide shoppers who want both molecules disclosed at fair prices and will do their own diligence on the pharmacy.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | CoreAge Rx | Piper |
|---|---|---|
| Cost-Efficiency Index | 94/100 | 82/100 |
| Semaglutide / mo | $149/mo | $135/mo |
| Tirzepatide / mo | $349/mo | $199/mo |
| Semaglutide / yr (modeled) | $1,788 | $1,620 |
| Tirzepatide / yr (modeled) | $4,188 | $2,388 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank on the board | #1 | #22 |
CoreAge Rx
94/100Where the value is
- Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
- Both compounded semaglutide and tirzepatide on one account at published prices
- Available in all 50 states — no coverage gamble
The tradeoffs
- Not the rock-bottom sticker price — cheaper teaser tiers exist (Direct GLP lists $65, Ondra $93 on semaglutide)
- No FDA-approved brand-name option (compounded only)
Piper
82/100Where the value is
- Both molecules disclosed — $135 semaglutide / $199 tirzepatide — for clean cost modeling
- Nationwide all-50 access with predictable flat pricing
- Straightforward to model for a full year
The tradeoffs
- Not LegitScript-certified, so pharmacy oversight is harder to verify
- Compounded only — no brand-name or oral route
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.