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WeighLab

Actin vs Cielo

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Actin

Provider comparison

Shoppers who want compounded semaglutide or tirzepatide at a price shown before the questionnaire, with weight, hormone and longevity care on one account.

Semaglutide / month
$169/moMonth-to-month (compounded; $143/mo on a 3-month plan, $116/mo on a 6-month plan; no membership fee)
Tirzepatide / month
$269/moMonth-to-month (compounded; $209/mo on a 3-month plan, $166/mo on a 6-month plan; no membership fee)
Index 67/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Actin pricing Read review

Cielo

Provider comparison

Shoppers who want one price at every dose and can choose between a monthly plan and cheaper 3-, 6- or 12-month plans.

Semaglutide / month
$139/moAll doses, monthly plan, compounded; $99/mo on a 3-month plan, $89/mo on 6 months, $84/mo on 12 months
Tirzepatide / month
$189/moAll doses, monthly plan, compounded; $149/mo on a 3-month plan, $129/mo on 6 months, $119/mo on 12 months
Index 66/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Cielo pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Actin has the higher Cost-Efficiency Index: 67/100 versus 66/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Actin

Cielo

Semaglutide / month
Actin: $169/moMonth-to-month (compounded; $143/mo on a 3-month plan, $116/mo on a 6-month plan; no membership fee)
Cielo: $139/moAll doses, monthly plan, compounded; $99/mo on a 3-month plan, $89/mo on 6 months, $84/mo on 12 months
Tirzepatide / month
Actin: $269/moMonth-to-month (compounded; $209/mo on a 3-month plan, $166/mo on a 6-month plan; no membership fee)
Cielo: $189/moAll doses, monthly plan, compounded; $149/mo on a 3-month plan, $129/mo on 6 months, $119/mo on 12 months
Semaglutide / year (modeled)
Actin: $2,028
Cielo: $1,668
Tirzepatide / year (modeled)
Actin: $3,228
Cielo: $2,268
State availability
Actin: Coverage not published
Cielo: Coverage not published
Oral / sublingual option listed
Actin: Not listed
Cielo: Not listed
Brand-name access listed
Actin: Not confirmed
Cielo: Not confirmed
Provider facts checked
Actin: October 2026
Cielo: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Actin

Shoppers who want compounded semaglutide or tirzepatide at a price shown before the questionnaire, with weight, hormone and longevity care on one account.

Reasons to consider it

  • Prices published on each product page before you start: semaglutide $169/mo month-to-month, tirzepatide $269/mo
  • No membership fee; supplies, dose adjustments and shipping are included
  • Names its pharmacies (The Pharmacy Hub, GreenwichRX, Hallandale Pharmacy) and its medical group (Beluga Health, P.A.)

What to weigh up

  • The 'starting at' prices ($116 and $166) are six-month plan rates
  • All compounded; no brand-name Wegovy or Zepbound
  • All sales are final and fees aren't refunded

Compounded drugs are not FDA-approved. Understand the medication options.

Check Actin pricing Read the full Actin review

Cielo

Shoppers who want one price at every dose and can choose between a monthly plan and cheaper 3-, 6- or 12-month plans.

Reasons to consider it

  • Flat pricing regardless of dose for both semaglutide and tirzepatide, avoiding per-mg price escalation during titration
  • Free physician consult and free shipping stated as included
  • Claims 'Every batch tested', at least asserting quality-control testing exists

What to weigh up

  • The 3-, 6- and 12-month plans don't say whether they're paid up front or billed monthly, so ask before you pick one
  • Compounded semaglutide and tirzepatide only, with no brand-name option
  • The site doesn't name its pharmacy, medical director or prescribers

Compounded drugs are not FDA-approved. Understand the medication options.

Check Cielo pricing Read the full Cielo review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

ActinCielo
Normalized Cost/Month
Actin:
72/100
Cielo:
86/100
Price Transparency
Actin:
92/100
Cielo:
94/100
Nationwide Access
Actin:
24/100
Cielo:
24/100
Formulation Options
Actin:
66/100
Cielo:
66/100
Clinical Oversight
Actin:
79/100
Cielo:
80/100
Contract Flexibility
Actin:
67/100
Cielo:
25/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.