Head-to-head · Cost-Efficiency Index
CoreAge Rx vs Actin
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
CoreAge Rx
Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.
Visit CoreAge RxActin
Cost-first shoppers who want affordable compounded semaglutide with B12 enhancement.
Visit ActinThe verdict
CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 47. Best value on the board: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. Actin still earns a C — Cost-first shoppers who want affordable compounded semaglutide with B12 enhancement.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | CoreAge Rx | Actin |
|---|---|---|
| Cost-Efficiency Index | 94/100 | 47/100 |
| Semaglutide / mo | $149/mo | $169/mo (compounded) |
| Tirzepatide / mo | $349/mo | Not disclosed |
| Semaglutide / yr (modeled) | $1,788 | $2,028 |
| Tirzepatide / yr (modeled) | $4,188 | — |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank on the board | #1 | #402 |
CoreAge Rx
94/100Where the value is
- Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
- Both compounded semaglutide and tirzepatide on one account at published prices
- Available in all 50 states — no coverage gamble
The tradeoffs
- Not the rock-bottom sticker price — cheaper teaser tiers exist (Direct GLP lists $65, Ondra $93 on semaglutide)
- No FDA-approved brand-name option (compounded only)
Actin
47/100Where the value is
- Semaglutide paired with B12 for added energy support
- Transparent pricing — exact cost shown upfront with no hidden fees
- Competitive pricing from $116/mo on the 6-month plan ($169/mo month-to-month)
The tradeoffs
- Semaglutide only — no tirzepatide or liraglutide
- No visible LegitScript or PCAB accreditation
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.