Head-to-head · Cost-Efficiency Index
Zera Health vs MangoRx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Zera Health
Shoppers who want a named 503A pharmacy and full 50-state coverage at a moderate compounded price.
Visit Zera HealthMangoRx
Men who want a needle-free semaglutide tablet at one published monthly price.
Visit MangoRxThe verdict
Zera Health and MangoRx tie on the Cost-Efficiency Index at 61/100, so neither wins outright on the numbers, so choose on fit. Zera Health: Shoppers who want a named 503A pharmacy and full 50-state coverage at a moderate compounded price. MangoRx: Men who want a needle-free semaglutide tablet at one published monthly price.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Zera Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Zera Health | MangoRx |
|---|---|---|
| Cost-Efficiency Index | 61/100 | 61/100 |
| Semaglutide / mo | Not disclosed | $299/moOral dissolving tablet, 30-day supply, compounded |
| Tirzepatide / mo | Not disclosed | Not offered |
| Semaglutide / yr (modeled) | — | $3,588 |
| Tirzepatide / yr (modeled) | — | — |
| Coverage | All 50 states | Not published |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #287 | #289 |
Zera Health
61/100Where the value is
- Named dispensing pharmacy — Strive Pharmacy, a 503A compounder — disclosed in the footer
- LegitScript Certified badge displayed
- States coverage across all 50 states with no exclusions listed
The tradeoffs
- The advertised '$149' semaglutide price is explicitly a first-month-only rate; the standing price is $179/mo
- Tirzepatide's '$199/mo' figure has no first-month/standing clarifier on the page, unlike semaglutide, so it's unclear if it will also step up after month one
MangoRx
61/100Where the value is
- Slim is priced openly on its product page at $299 for a month's supply, with the price locked in and no hidden fees
- A needle-free option: a mint-flavored tablet that dissolves in the mouth, with vitamin B6 added for nausea
- Free provider visits and free shipping on all orders
The tradeoffs
- Only semaglutide in one oral form; no tirzepatide, no injection and no brand-name option
- An oral compounded tablet is a different product from the injections most GLP-1 programs sell, and the site doesn't explain how its doses compare
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.