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WeighLab

YourEra vs Defy Medical

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

YourEra

Affiliate partner

Shoppers comfortable starting an intake to see the price, who will confirm what month two costs before paying.

Semaglutide / month
Not disclosedAdvertised from $79/mo with a new-patient coupon; the standing monthly rate shows only after you enter an email
Tirzepatide / month
Not disclosedAdvertised from $159/mo with a new-patient coupon; the standing monthly rate shows only after you enter an email
Index 43/100 · Grade CChecked August 2026

Defy Medical

Provider comparison

Men already in TRT or hormone care who want to add a GLP-1 with the same clinic, rather than shoppers comparing GLP-1 prices alone.

Semaglutide / month
Not disclosed
Tirzepatide / month
Not disclosed
Index 43/100 · Grade CChecked August 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 43/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

YourEra

Defy Medical

Semaglutide / month
YourEra: Not disclosedAdvertised from $79/mo with a new-patient coupon; the standing monthly rate shows only after you enter an email
Defy Medical: Not disclosed
Tirzepatide / month
YourEra: Not disclosedAdvertised from $159/mo with a new-patient coupon; the standing monthly rate shows only after you enter an email
Defy Medical: Not disclosed
Semaglutide / year (modeled)
YourEra: —
Defy Medical: —
Tirzepatide / year (modeled)
YourEra: —
Defy Medical: —
State availability
YourEra: Coverage not published
Defy Medical: Coverage not published
Oral / sublingual option listed
YourEra: Not listed
Defy Medical: Yes
Brand-name access listed
YourEra: Not confirmed
Defy Medical: Not confirmed
Provider facts checked
YourEra: August 2026
Defy Medical: August 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

YourEra

Shoppers comfortable starting an intake to see the price, who will confirm what month two costs before paying.

Reasons to consider it

  • No membership-fee structure; the site markets "No Hidden Costs" and says there are no long-term contracts, with pause or cancel from the patient portal
  • Prescriptions are "issued only if deemed medically appropriate" after evaluation by licensed US clinicians, stated plainly
  • Names its legal entity in its Terms of Service (YourEra, Inc. and/or its subsidiaries)

What to weigh up

  • The homepage advertises semaglutide "from $79/mo" and tirzepatide "from $159/mo" with no plan length attached, and every sign-up button on it carries a 20% new-patient coupon, so neither figure is what a month-to-month plan costs after the first month
  • The price you will pay appears only after you enter an email address in the intake, so the standing monthly rate can't be checked before you sign up
  • No pharmacy partner is named, only "the Pharmacies" generically, per the Terms of Service

Defy Medical

Men already in TRT or hormone care who want to add a GLP-1 with the same clinic, rather than shoppers comparing GLP-1 prices alone.

Reasons to consider it

  • Named, credentialed Medical Director (Dr. Justin Saya)
  • Large third-party review base (3,999 Trustpilot reviews, 5-star average)
  • Offers both semaglutide and tirzepatide alongside broader men's-health services

What to weigh up

  • GLP-1 is clearly a secondary offering bolted onto a primarily TRT/hormone-optimization practice, not its core focus
  • Zero pricing disclosed on its site -- fully gated behind quiz/consultation
  • No LegitScript certification

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

YourEraDefy Medical
Normalized Cost/Month
YourEra:
45/100
Defy Medical:
45/100
Price Transparency
YourEra:
20/100
Defy Medical:
20/100
Nationwide Access
YourEra:
24/100
Defy Medical:
24/100
Formulation Options
YourEra:
66/100
Defy Medical:
56/100
Clinical Oversight
YourEra:
71/100
Defy Medical:
80/100
Contract Flexibility
YourEra:
47/100
Defy Medical:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.