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WeighLab

CoreAge Rx vs Defy Medical

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Defy Medical

Provider comparison

Men already in TRT or hormone care who want to add a GLP-1 with the same clinic, rather than shoppers comparing GLP-1 prices alone.

Semaglutide / month
Not disclosed
Tirzepatide / month
Not disclosed
Index 43/100 · Grade CChecked August 2026

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The comparison in brief

CoreAge Rx has the higher Cost-Efficiency Index: 94/100 versus 43/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

CoreAge Rx
All 50 states
Defy Medical
Coverage not published

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

CoreAge Rx

Defy Medical

Semaglutide / month
CoreAge Rx: $99/mo
Defy Medical: Not disclosed
Tirzepatide / month
CoreAge Rx: $149/mo
Defy Medical: Not disclosed
Semaglutide / year (modeled)
CoreAge Rx: $1,188
Defy Medical: —
Tirzepatide / year (modeled)
CoreAge Rx: $1,788
Defy Medical: —
State availability
CoreAge Rx: All 50 states
Defy Medical: Coverage not published
Oral / sublingual option listed
CoreAge Rx: Not listed
Defy Medical: Yes
Brand-name access listed
CoreAge Rx: Not confirmed
Defy Medical: Not confirmed
Provider facts checked
CoreAge Rx: October 2026
Defy Medical: August 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

CoreAge Rx

Anyone who wants one flat monthly price they can plan a full year around, on either molecule, without signing a contract.

Reasons to consider it

  • One price at every dose: semaglutide is $99 from 0.25 mg up to 2.5 mg, and tirzepatide is $149 from 2.5 mg up to 15 mg
  • No membership fee, no insurance needed and no long-term contract, and the price you lock in at checkout stays put as your dose rises
  • If the doctor decides a prescription isn't right for you, CoreAge refunds the medication portion of your payment

What to weigh up

  • Some programs we track publish lower semaglutide prices. Compare billing terms, dose pricing and required fees before choosing.
  • You pay before the doctor reviews your case, and if you aren't approved the FAQ promises a 100% refund while the refund policy keeps a $50 to $100 consultation fee
  • All sales are final once medication ships, because state and federal law don't allow medication returns

Defy Medical

Men already in TRT or hormone care who want to add a GLP-1 with the same clinic, rather than shoppers comparing GLP-1 prices alone.

Reasons to consider it

  • Named, credentialed Medical Director (Dr. Justin Saya)
  • Large third-party review base (3,999 Trustpilot reviews, 5-star average)
  • Offers both semaglutide and tirzepatide alongside broader men's-health services

What to weigh up

  • GLP-1 is clearly a secondary offering bolted onto a primarily TRT/hormone-optimization practice, not its core focus
  • Zero pricing disclosed on its site -- fully gated behind quiz/consultation
  • No LegitScript certification

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

CoreAge RxDefy Medical
Normalized Cost/Month
CoreAge Rx:
93/100
Defy Medical:
45/100
Price Transparency
CoreAge Rx:
97/100
Defy Medical:
20/100
Nationwide Access
CoreAge Rx:
98/100
Defy Medical:
24/100
Formulation Options
CoreAge Rx:
84/100
Defy Medical:
56/100
Clinical Oversight
CoreAge Rx:
90/100
Defy Medical:
80/100
Contract Flexibility
CoreAge Rx:
95/100
Defy Medical:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

Choose a different comparison

Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.