Head-to-head · Cost-Efficiency Index
Willow vs Enara Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Willow
Cost-first shoppers who want an oral-tablet GLP-1 option at the same price as the injectable, with no annual commitment.
Visit WillowEnara Health
Patients whose insurance is in-network and who want a clinic-based (not pure cash-pay compounded) GLP-1 program.
Visit Enara HealthThe verdict
Willow takes it, leading the Cost-Efficiency Index 49 to 48. Willow is a direct-to-consumer telehealth provider offering compounded semaglutide and tirzepatide in both injectable and oral-tablet form at identical prices per format. Enara Health still earns a C — Patients whose insurance is in-network and who want a clinic-based (not pure cash-pay compounded) GLP-1 program.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Willow.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Willow | Enara Health |
|---|---|---|
| Cost-Efficiency Index | 49/100 | 48/100 |
| Semaglutide / mo | Not disclosed | Not disclosed |
| Tirzepatide / mo | Not disclosed | Not disclosed |
| Semaglutide / yr (modeled) | — | — |
| Tirzepatide / yr (modeled) | — | — |
| Coverage | Coverage not published | 6 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #429 | #435 |
Willow
49/100Where the value is
- Oral tablet formulations of both semaglutide and tirzepatide, priced identically to the injectable versions ($299/mo and $399/mo respectively) — a genuine format choice most compounded-drug competitors don't offer
- Month-to-month billing with no prepay or annual term required to get the advertised rate
- Named physician team publicly listed, including Chief Medical Officer Dr. Michael Green, MD, plus 11+ other credentialed MDs/DOs
The tradeoffs
- Only 34 states served — notably narrower than WeightlessRx's 49-state footprint; residents of the other 16 states plus DC are excluded
- Site states medication cost 'varies by dosage and prescription' but never discloses what a higher maintenance dose actually costs beyond the $299/$399 starting figures
Enara Health
48/100Where the value is
- In-network with major insurers (UHC, BCBS, Aetna, Cigna, Humana) -- can be far cheaper than cash-pay for covered patients
- Cites outcomes data ('22% weight loss at 18 months' with GLP-1s)
- Partner clinic network model rather than pure telehealth-only
The tradeoffs
- Only available via partner clinics in 6 (unnamed) states -- not nationwide
- No cash-pay price list -- unusable for comparison shoppers without matching insurance
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.