Head-to-head · Cost-Efficiency Index
Tuyo Health vs Center for Medical Weight Loss (CMWL)
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Tuyo Health
Shoppers who want a low advertised floor price and are willing to confirm the actual dose-tier cost before committing.
Visit Tuyo HealthCenter for Medical Weight Loss (CMWL)
Shoppers wanting a long-established national weight-loss brand with all-in bundled pricing.
Visit Center for Medical Weight Loss (CMWL)The verdict
Tuyo Health and Center for Medical Weight Loss (CMWL) tie on the Cost-Efficiency Index at 57/100, so neither wins outright on the numbers. For most shoppers we'd start with Tuyo Health (ranked #298, a hair above #300) — Shoppers who want a low advertised floor price and are willing to confirm the actual dose-tier cost before committing. But Center for Medical Weight Loss (CMWL) is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Tuyo Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Tuyo Health | Center for Medical Weight Loss (CMWL) |
|---|---|---|
| Cost-Efficiency Index | 57/100 | 57/100 |
| Semaglutide / mo | $155/mo (starting dose, compounded) | $116/mo (starting dose, compounded) |
| Tirzepatide / mo | $279/mo (starting dose, compounded) | $159/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $1,860 | $1,392 |
| Tirzepatide / yr (modeled) | $3,348 | $1,908 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #298 | #300 |
Tuyo Health
57/100Where the value is
- Quarterly lab work is explicitly bundled into the compounded-track price, unlike sites that omit lab monitoring entirely
- Offers both compounded and branded (insurance-eligible) tracks on the same platform
- LegitScript certified
The tradeoffs
- Both headline prices are explicit 'as low as' floors with no dose-tier table published — the real cost for a titrated-up dose is unknown from the site
- No compounding pharmacy or individual prescriber/medical director named anywhere on the page
Regulatory note: the FDA issued a warning letter to Tuyo Health, Inc. dba Tuyo Health in September 2025. We still list and link to Tuyo Health; you should know the letter is on the public record before you decide.
Center for Medical Weight Loss (CMWL)
57/100Where the value is
- Long-established, recognizable national brand
- All-in pricing with no separate membership fee
- Ships to all 50 states
The tradeoffs
- No individual medical director or compounding pharmacy named
- Confusing plan structure -- the '3-month plan' is priced higher per month than the base plan, opposite of typical prepay discounts
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.