Head-to-head · Cost-Efficiency Index
CoreAge Rx vs Tuyo Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
CoreAge Rx
Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.
Visit CoreAge RxTuyo Health
Shoppers who want a low advertised floor price and are willing to confirm the actual dose-tier cost before committing.
Visit Tuyo HealthThe verdict
CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 57. Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. Tuyo Health still earns a C — Shoppers who want a low advertised floor price and are willing to confirm the actual dose-tier cost before committing.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | CoreAge Rx | Tuyo Health |
|---|---|---|
| Cost-Efficiency Index | 94/100 | 57/100 |
| Semaglutide / mo | $99/mo | $155/mo (starting dose, compounded) |
| Tirzepatide / mo | $149/mo | $279/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $1,188 | $1,860 |
| Tirzepatide / yr (modeled) | $1,788 | $3,348 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #1 | #298 |
CoreAge Rx
94/100Where the value is
- Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
- Both compounded semaglutide and tirzepatide on one account at published prices
- Available in all 50 states — no coverage gamble
The tradeoffs
- Not the rock-bottom sticker price — 30 of the 381 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
- No FDA-approved brand-name option (compounded only)
Tuyo Health
57/100Where the value is
- Quarterly lab work is explicitly bundled into the compounded-track price, unlike sites that omit lab monitoring entirely
- Offers both compounded and branded (insurance-eligible) tracks on the same platform
- LegitScript certified
The tradeoffs
- Both headline prices are explicit 'as low as' floors with no dose-tier table published — the real cost for a titrated-up dose is unknown from the site
- No compounding pharmacy or individual prescriber/medical director named anywhere on the page
Regulatory note: the FDA issued a warning letter to Tuyo Health, Inc. dba Tuyo Health in September 2025. We still list and link to Tuyo Health; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.