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WeighLab

Trillium Meds vs OnlyRx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Trillium Meds

Provider comparison

Shoppers who want compounded GLP-1 in all 50 states with a real month-to-month option and a cheaper 3-month prepay.

Semaglutide / month
$159/moAll doses, compounded
Tirzepatide / month
$199/moAny dose, compounded; pharmacy-specific plans
Index 78/100 · Grade CChecked October 2026

OnlyRx

Provider comparison

Shoppers who want a 50-state marketplace with multiple pharmacy options and named prescribers.

Semaglutide / month
$179/moStarting dose, compounded
Tirzepatide / month
$249/moStarting dose, compounded
Index 77/100 · Grade CChecked October 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Trillium Meds has the higher Cost-Efficiency Index: 78/100 versus 77/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Trillium Meds

OnlyRx

Semaglutide / month
Trillium Meds: $159/moAll doses, compounded
OnlyRx: $179/moStarting dose, compounded
Tirzepatide / month
Trillium Meds: $199/moAny dose, compounded; pharmacy-specific plans
OnlyRx: $249/moStarting dose, compounded
Semaglutide / year (modeled)
Trillium Meds: $1,908
OnlyRx: $2,148
Tirzepatide / year (modeled)
Trillium Meds: $2,388
OnlyRx: $2,988
State availability
Trillium Meds: All 50 states
OnlyRx: All 50 states
Oral / sublingual option listed
Trillium Meds: Not listed
OnlyRx: Yes
Brand-name access listed
Trillium Meds: Not confirmed
OnlyRx: Yes
Provider facts checked
Trillium Meds: October 2026
OnlyRx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Trillium Meds

Shoppers who want compounded GLP-1 in all 50 states with a real month-to-month option and a cheaper 3-month prepay.

Reasons to consider it

  • Names pharmacy partners and displays their plan totals, formulations and shipping restrictions
  • One-month and prepaid options are published before intake
  • One-month semaglutide $159 and tirzepatide $199 offers cover any prescribed dose at several pharmacies

What to weigh up

  • Lower prepaid averages require buying multiple months at once; plans and state restrictions differ by pharmacy
  • The pharmacy card and actual fulfillment pharmacy can differ; Hyalo lists NewLife and Nova lists White Label as fulfillment partners
  • Pharmacy choice depends on availability and can be changed by the provider or pharmacy

OnlyRx

Shoppers who want a 50-state marketplace with multiple pharmacy options and named prescribers.

Reasons to consider it

  • Says it serves all 50 states
  • Names physicians at Lion MD with public NPI numbers
  • Lists four pharmacy partners with contact information

What to weigh up

  • The banner still calls $179 a Summer Promo, while product cards say starting at; confirm the ongoing rate
  • No dose-by-dose price list is published
  • Ask which of the four pharmacy partners will fill your prescription

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Trillium MedsOnlyRx
Normalized Cost/Month
Trillium Meds:
80/100
OnlyRx:
68/100
Price Transparency
Trillium Meds:
97/100
OnlyRx:
84/100
Nationwide Access
Trillium Meds:
86/100
OnlyRx:
86/100
Formulation Options
Trillium Meds:
66/100
OnlyRx:
90/100
Clinical Oversight
Trillium Meds:
89/100
OnlyRx:
72/100
Contract Flexibility
Trillium Meds:
25/100
OnlyRx:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.