Head-to-head · Cost-Efficiency Index
Teleios Health vs Yes Clinic
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Teleios Health
Shoppers comfortable calling or messaging before committing, since public pricing detail is minimal.
Visit Teleios HealthYes Clinic
Shoppers who can pay for three months at once and want a price that won't rise as their dose goes up.
Visit Yes ClinicThe verdict
Teleios Health and Yes Clinic tie on the Cost-Efficiency Index at 65/100, so neither wins outright on the numbers, so choose on fit. Teleios Health: Shoppers comfortable calling or messaging before committing, since public pricing detail is minimal. Yes Clinic: Shoppers who can pay for three months at once and want a price that won't rise as their dose goes up.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Teleios Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Teleios Health | Yes Clinic |
|---|---|---|
| Cost-Efficiency Index | 65/100 | 65/100 |
| Semaglutide / mo | $99/moAll doses, compounded | $129/mo3-month plan, billed $387 upfront, same price at every dose, compounded |
| Tirzepatide / mo | Not disclosed | $149/mo3-month plan, billed $447 upfront, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $1,188 | $1,548 |
| Tirzepatide / yr (modeled) | — | $1,788 |
| Coverage | Coverage not published | Not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #209 | #211 |
Teleios Health
65/100Where the value is
- Advertises a low $99/mo headline starting price, undercutting most compounded-GLP-1 competitors on paper
- Explicitly brands itself as 'physician-led,' setting an expectation of clinician oversight
- Discloses the standard compounded-medication FDA disclaimer up front rather than burying it
The tradeoffs
- No dose amount, drug, or inclusion breakdown is published for the $99/mo figure
- No visit fee, membership fee, or shipping fee disclosure
Yes Clinic
65/100Where the value is
- Every plan price is on the product pages with no quiz or account: semaglutide $387 for 3 months or $699 for 6, tirzepatide $447 or $894
- The price stays the same at every dose, and the online consultation, shipping and membership are all included at $0
- If a provider declines to prescribe, you aren't charged for medication, and a 6-month plan refunds months 4 to 6 if they aren't approved
The tradeoffs
- There is no single-month plan: the cheapest way in is three months paid upfront
- The homepage says GLP-1 programs start "From $199/month" and mentions monthly plan rates, while the product pages show only $129 and $149 a month on 3- and 6-month plans
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.