Head-to-head · Cost-Efficiency Index
System Labs vs WellMedr
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
System Labs
People looking for NAD+, sermorelin or a MIC+B12 injection through a clinician; anyone after a GLP-1 prescription needs a different provider.
Visit System LabsWellMedr
Shoppers who will complete a medical intake before they see a price, in exchange for a brand Ozempic or Zepbound lane and an eight-SKU microdose line on the same account as the compounded plan.
Visit WellMedrThe verdict
System Labs takes it, leading the Cost-Efficiency Index 59 to 54. System Labs is a peptide and longevity telehealth service selling NAD+, glutathione, sermorelin and a MIC+B12 injection; it doesn't sell semaglutide, tirzepatide or any GLP-1 medication. WellMedr still earns a C — Shoppers who will complete a medical intake before they see a price, in exchange for a brand Ozempic or Zepbound lane and an eight-SKU microdose line on the same account as the compounded plan.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs System Labs.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | System Labs | WellMedr |
|---|---|---|
| Cost-Efficiency Index | 59/100 | 54/100 |
| Semaglutide / mo | Not disclosed | Not disclosedSale price only, no standing rate |
| Tirzepatide / mo | Not disclosed | Not disclosed"Starting at" only, no standing rate |
| Semaglutide / yr (modeled) | — | — |
| Tirzepatide / yr (modeled) | — | — |
| Coverage | All 50 states | 50 states claimed, no list published |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Yes |
| Rank here | #326 | #367 |
System Labs
59/100Where the value is
- Prices are listed up front, such as MIC+B12 at $89 a month and NAD+ at $149 a month ($89 for the first month)
- Names its compounding pharmacy, The Pharmacy Hub in Miami, in its FAQ
- Names its medical advisors on the homepage and says it serves all 50 states
The tradeoffs
- It doesn't sell semaglutide, tirzepatide or any other GLP-1 medication
- Refunds aren't offered once services are rendered or a prescription is ordered
WellMedr
54/100Where the value is
- The compounding caveat sits ON the pricing page beside the plan cards rather than in a footer: "Compounded medications are regulated by state Boards of Pharmacy, but are not evaluated by the FDA for safety or efficacy," printed with explicit thyroid C-cell tumor and medullary thyroid carcinoma warnings
- Both halves of the supply chain are named and checkable — OpenLoop Healthcare Partners, PC and its state professional corporations as the prescribing group in the telehealth consent, and Mycelium Pharmacy as the fulfillment pharmacy in the HIPAA notice
- The tirzepatide card states "Same price regardless of dosage," so titrating up does not re-price that plan — the single most common way a cheap first month becomes an expensive fourth one
The tradeoffs
- No standing month-to-month rate is published for either compounded drug. The monthly-plan cards say "Starting At $49 a month" and "Starting At $89 a month" under a "Fall sale discount" banner, the same page offers new customers "$150 off for Life," and neither says what the plan costs without them; the intake asks for your height and weight before it shows any price
- The billing cycle is stated two ways: the plan cards say medication is "shipped every 4 weeks" while the Refund and Cancellation Policy says the subscription "will automatically renew every 21 days." One is 13 charges a year and the other about 17 — neither is the 12 that "a month" implies
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.