Head-to-head · Cost-Efficiency Index
Synergy Rx vs DoctorAdam
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Synergy Rx
People who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by inquiry.
Visit Synergy RxDoctorAdam
Shoppers who want a needle-free oral GLP-1 with named prescribers, in the 47 states DoctorAdam actually serves.
Visit DoctorAdamThe verdict
DoctorAdam takes it, leading the Cost-Efficiency Index 74 to 72. DoctorAdam is a Shopify-storefront telehealth company selling compounded oral (sublingual) and injectable semaglutide and tirzepatide plus NAD+/glutathione add-ons, prescribed by a named roster of six MD/NP prescribers. Synergy Rx still earns a C — People who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by inquiry.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs DoctorAdam.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Synergy Rx | DoctorAdam |
|---|---|---|
| Cost-Efficiency Index | 72/100 | 74/100 |
| Semaglutide / mo | From $199/mo | $129/mo (starting dose, compounded oral) |
| Tirzepatide / mo | From $349/mo | $199/mo (starting dose, compounded oral) |
| Semaglutide / yr (modeled) | $2,388 | $1,548 |
| Tirzepatide / yr (modeled) | $4,188 | $2,388 |
| Coverage | Not disclosed | 44 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Yes | Compounded only |
| Rank here | #53 | #58 |
Synergy Rx
72/100Where the value is
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate, not compounded only
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- A $100 welcome credit applied at checkout, and FSA/HSA eligible
The tradeoffs
- Prices are published as bare “Starting at” figures with no billing cycle or term attached, so a full-year cost still cannot be modeled before an inquiry
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
DoctorAdam
74/100Where the value is
- Names six actual prescribers with credentials — unusually transparent for a Shopify-based storefront
- Needle-free oral tablet option for both semaglutide (from $129) and tirzepatide (from $199)
- Flat 'no hidden fees' pricing framing, with free 2-3 business day shipping
The tradeoffs
- The homepage claims 'Delivery Across All 50 States' but the site's own FAQ state list is 47 states plus DC — New Jersey, Mississippi, and Alaska are excluded
- Injectable dose-tier pricing could not be verified live in this pass (repeated 429 errors on the product pages); only the oral 'from' price is confirmed
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.