Head-to-head · Cost-Efficiency Index
Synergy Rx vs Aspen
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Synergy Rx
People who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by inquiry.
Visit Synergy RxAspen
Cost-first shoppers who want wanting one flat price regardless of whether treatment ends up being semaglutide or tirzepatide, if willing to commit to 3 months.
Visit AspenThe verdict
Aspen takes it, leading the Cost-Efficiency Index 74 to 72. Aspen Health (startaspen.com) is a cash-pay telehealth platform spanning weight loss, hair health, longevity, and sexual wellness. Synergy Rx still earns a C — People who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by inquiry.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Aspen.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Synergy Rx | Aspen |
|---|---|---|
| Cost-Efficiency Index | 72/100 | 74/100 |
| Semaglutide / mo | From $199/mo | $179/mo (all doses, compounded) |
| Tirzepatide / mo | From $349/mo | $179/mo (all doses, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $2,148 |
| Tirzepatide / yr (modeled) | $4,188 | $2,148 |
| Coverage | Not disclosed | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #53 | #57 |
Synergy Rx
72/100Where the value is
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate, not compounded only
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- A $100 welcome credit applied at checkout, and FSA/HSA eligible
The tradeoffs
- Prices are published as bare “Starting at” figures with no billing cycle or term attached, so a full-year cost still cannot be modeled before an inquiry
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
Aspen
74/100Where the value is
- One transparent, dose-independent flat price ($179/mo) covers either the semaglutide or tirzepatide path, avoiding the tirzepatide surcharge most compounded competitors charge
- Price stated to be all-in: provider consultation, custom dosing, medication, and free delivery bundled with no listed add-on fees
- No insurance required, cash-pay simplicity
The tradeoffs
- The bold '$179/mo' headline omits its own fine-print condition — a 3-month commitment — visible only in small text directly beneath the price
- Almost nothing else is disclosed on the public site: no states-served list, no named medical director or prescriber, no named pharmacy, and no LegitScript certification found
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.