Head-to-head · Cost-Efficiency Index
Strive Pharmacy vs Joi + Blokes
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Strive Pharmacy
Patients whose OWN clinic already prescribes through Strive — not for shoppers looking to start a new GLP-1 prescription directly.
Visit Strive PharmacyJoi + Blokes
Patients already on Joi or Blokes hormone programs who want GLP-1 added under the same clinician relationship, and are comfortable with a 3-month billing commitment.
Visit Joi + BlokesThe verdict
Strive Pharmacy takes it, leading the Cost-Efficiency Index 53 to 52. Strive Pharmacy is a 503A/503B compounding pharmacy that primarily serves OTHER healthcare providers and clinics — not a direct-to-consumer telehealth site. Joi + Blokes still earns a C — Patients already on Joi or Blokes hormone programs who want GLP-1 added under the same clinician relationship, and are comfortable with a 3-month billing commitment.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Strive Pharmacy.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Strive Pharmacy | Joi + Blokes |
|---|---|---|
| Cost-Efficiency Index | 53/100 | 52/100 |
| Semaglutide / mo | Not disclosed | $199/mo (quarterly plan, compounded) |
| Tirzepatide / mo | Not disclosed | $299/mo (quarterly plan, compounded) |
| Semaglutide / yr (modeled) | — | $2,388 |
| Tirzepatide / yr (modeled) | — | $3,588 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #381 | #384 |
Strive Pharmacy
53/100Where the value is
- Is a real, named 503A/503B compounding pharmacy rather than an anonymous telehealth brand
- Transparent about being provider-facing first: the site does not pretend to be a consumer GLP-1 shopping destination
The tradeoffs
- Not a direct-to-consumer option at all — there is no way for a new patient to get a semaglutide or tirzepatide prescription by visiting strivepharmacy.com; you need an existing prescriber relationship with a clinic that already partners with Strive
- No consumer pricing for any GLP-1 product exists anywhere on the site
Joi + Blokes
52/100Where the value is
- Named Medical Director, Dr. Melissa Loseke, DO, plus a named Head Nurse Practitioner and two named Medical Advisors — real clinical attribution not disclosed by most competitors in this batch
- Separate gender-specific programs (Joi for women, Blokes for men) built around hormone health, with GLP-1 added as an integrated option alongside testosterone/perimenopause protocols
- For FDA-approved GLP-1/GIP medications specifically, insurance is accepted and the prescription routes to the patient's own local pharmacy rather than a mail-order compounder
The tradeoffs
- Billed in 3-month blocks, not month-to-month — the $99/$149 first-month price is promotional, and the real standing cost from month 2 is $199 (semaglutide) or $299 (tirzepatide)
- New York and New Jersey residents are explicitly called out as paying different pricing, but the site does not state the amount
Regulatory note: the FDA issued a warning letter to Joi and Blokes dba Joi + Blokes in June 2026. We still list and link to Joi + Blokes; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.