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Head-to-head · Cost-Efficiency Index

SkyRx vs TeleDocs360

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #346

SkyRx

Shoppers willing to commit and prepay a full year upfront in exchange for a lower blended monthly rate.

Visit SkyRx
VS
Grade C · #347

TeleDocs360

Shoppers who want dose-tier pricing spelled out clearly upfront rather than a vague 'starting at' hook.

Visit TeleDocs360

The verdict

Too close to callGrade C vs C

SkyRx and TeleDocs360 tie on the Cost-Efficiency Index at 55/100, so neither wins outright on the numbers. For most shoppers we'd start with SkyRx (ranked #346, a hair above #347) — Shoppers willing to commit and prepay a full year upfront in exchange for a lower blended monthly rate. But TeleDocs360 is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs SkyRx.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

51
39

Price Transparency

86
86

Nationwide Access

24
24

Formulation Options

64
77

Clinical Oversight

76
83

Contract Flexibility

20
20

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecSkyRxTeleDocs360
Cost-Efficiency Index55/10055/100
Semaglutide / mo$199/mo (compounded)$299/mo (compounded)
Tirzepatide / moNot disclosed$399/mo (compounded)
Semaglutide / yr (modeled)$2,388$3,588
Tirzepatide / yr (modeled)$4,788
CoverageCoverage not publishedCoverage not published
Oral / sublingualYesYes
Brand-name accessCompounded onlyCompounded only
Rank here#346#347

SkyRx

55/100

Where the value is

  • Simple, single headline price displayed on the weight-loss page
  • Claims LegitScript certification
  • Straightforward telehealth intake flow

The tradeoffs

  • The '$199/mo' price is a 12-month prepay rate, not a cancel-anytime monthly price -- a major disclosure trap
  • Tirzepatide not yet available ('coming soon'), so half the category is unpriced
Visit SkyRx

Full SkyRx review →

TeleDocs360

55/100

Where the value is

  • Rare in this category: pricing exceptions for higher doses are stated plainly, not buried
  • One flat all-inclusive price (doctor, medication, shipping)
  • Physician network (Impact Health) named

The tradeoffs

  • No individual medical director named, only the physician network
  • Compounding pharmacy partner not disclosed
Visit TeleDocs360

Full TeleDocs360 review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

Keep comparing

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