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Head-to-head · Cost-Efficiency Index

ShedRx (Shed) vs Vitara RX

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #4

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Visit ShedRx (Shed)
VS
Grade B+ · #10

Vitara RX

Value-first shoppers who want the cheapest all-50 price on both molecules and refuse to trade away pharmacy verification to get it.

Visit Vitara RX

The verdict

Too close to callGrade B+ vs B+

ShedRx (Shed) and Vitara RX tie on the Cost-Efficiency Index at 87/100, so neither wins outright on the numbers. For most shoppers we'd start with ShedRx (Shed) (ranked #4, a hair above #10) — People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price. But Vitara RX is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs ShedRx (Shed).

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
94

Price Transparency

74
87

Nationwide Access

92
96

Formulation Options

96
78

Clinical Oversight

84
86

Contract Flexibility

76
82

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecShedRx (Shed)Vitara RX
Cost-Efficiency Index87/10087/100
Semaglutide / mo$199/mo ($159 on a 12-month plan)$99/mo
Tirzepatide / mo$299/mo ($239 on a 12-month plan)$149/mo
Semaglutide / yr (modeled)$2,388$1,188
Tirzepatide / yr (modeled)$3,588$1,788
CoverageAll 50 statesAll 50 states
Oral / sublingualYesNo
Brand-name accessYesCompounded only
Rank here#4#10

ShedRx (Shed)

87/100

Where the value is

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee

The tradeoffs

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
Visit ShedRx (Shed)

Full ShedRx (Shed) review →

Vitara RX

87/100

Where the value is

  • $99 semaglutide and $149 tirzepatide — among the lowest combined prices in the ranking, and cheaper on tirzepatide than most sub-$100-sema rivals
  • Nationwide all-50 access with both molecules disclosed for clean year-one cost modeling
  • LegitScript-certified — budget pricing without the unverified-pharmacy asterisk that dogs the cheapest tier

The tradeoffs

  • Compounded only — no FDA-approved brand-name or oral/sublingual route
  • Lower-profile newcomer without a long public track record
Visit Vitara RX

Full Vitara RX review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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