Head-to-head · Cost-Efficiency Index
ShedRx vs Sprout Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
ShedRx
People who want the cheapest disclosed tirzepatide or an oral option without giving up a modelable flat price.
Visit ShedRxSprout Health
Price-first shoppers who want a fast, low-friction signup (often no labs or visit) at a verified pharmacy and don't need a named medical director.
Visit Sprout HealthThe verdict
ShedRx takes it, leading the Cost-Efficiency Index 87 to 85. The lowest published tirzepatide cost among our partners, plus an oral/sublingual route — strong cost-per-month for the needle-averse. Sprout Health still earns a B — Price-first shoppers who want a fast, low-friction signup (often no labs or visit) at a verified pharmacy and don't need a named medical director.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | ShedRx | Sprout Health |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 85/100 |
| Semaglutide / mo | $199/mo | $149/mo |
| Tirzepatide / mo | $299/mo | $199/mo |
| Semaglutide / yr (modeled) | $2,388 | $1,788 |
| Tirzepatide / yr (modeled) | $3,588 | $2,388 |
| Coverage | Not disclosed | Most states |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Yes |
| Rank on the board | #4 | #9 |
ShedRx
87/100Where the value is
- Lowest published tirzepatide price of our partner tier at $299/mo
- Offers oral/sublingual forms — more formulation options per dollar
- Both molecules disclosed for straightforward cost comparison
The tradeoffs
- States-served not disclosed
- Compounded only
Sprout Health
85/100Where the value is
- Well-priced compounded — $149 semaglutide / $199 tirzepatide — with LegitScript certification behind it
- Low-friction intake: no labs and often no synchronous visit required
- Offers a brand-name Wegovy/Zepbound path alongside the compounded 503A route
The tradeoffs
- No named medical director published, so clinical oversight is harder to attribute
- Availability is quiz-gated by state, so nationwide access isn't guaranteed until you qualify
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.