Head-to-head · Cost-Efficiency Index
ShedRx vs Breeze Meds
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
ShedRx
People who want the cheapest disclosed tirzepatide or an oral option without giving up a modelable flat price.
Visit ShedRxBreeze Meds
People who want to independently verify the clinicians and pharmacy behind their GLP-1 — and who'll pay a mid-market price for that paper trail plus FSA/HSA eligibility.
Visit Breeze MedsThe verdict
ShedRx takes it, leading the Cost-Efficiency Index 87 to 86. The lowest published tirzepatide cost among our partners, plus an oral/sublingual route — strong cost-per-month for the needle-averse. Breeze Meds still earns a B — People who want to independently verify the clinicians and pharmacy behind their GLP-1 — and who'll pay a mid-market price for that paper trail plus FSA/HSA eligibility.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | ShedRx | Breeze Meds |
|---|---|---|
| Cost-Efficiency Index | 87/100 | 86/100 |
| Semaglutide / mo | $199/mo | $199/mo |
| Tirzepatide / mo | $299/mo | $399/mo |
| Semaglutide / yr (modeled) | $2,388 | $2,388 |
| Tirzepatide / yr (modeled) | $3,588 | $4,788 |
| Coverage | Not disclosed | All 50 states |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank on the board | #4 | #5 |
ShedRx
87/100Where the value is
- Lowest published tirzepatide price of our partner tier at $299/mo
- Offers oral/sublingual forms — more formulation options per dollar
- Both molecules disclosed for straightforward cost comparison
The tradeoffs
- States-served not disclosed
- Compounded only
Breeze Meds
86/100Where the value is
- Best transparency of this partner batch — NPI-verifiable named physicians (Lion MD group), named dispensing pharmacies, and LegitScript certification
- All 50 states, with injectable semaglutide from $199/mo plus oral semaglutide (~$299) and oral tirzepatide (~$399) for the needle-averse
- FSA/HSA eligible, which trims the effective monthly cost
The tradeoffs
- Mid-to-higher per-month pricing — tirzepatide and the oral routes carry a premium over the cheapest all-50 rivals
- Compounded only — not FDA-approved brand-name medication
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.