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Head-to-head · Cost-Efficiency Index

ShedRx (Shed) vs Breeze Meds

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #4

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Visit ShedRx (Shed)
VS
Grade B · #6

Breeze Meds

People who want to independently verify the clinicians and pharmacy behind their GLP-1 — and who'll pay a mid-market price for that paper trail plus FSA/HSA eligibility.

Visit Breeze Meds

The verdict

Winner · ShedRx (Shed)Grade B+ vs B

ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 86. The widest set of formats in the ranking — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. Breeze Meds still earns a BPeople who want to independently verify the clinicians and pharmacy behind their GLP-1 — and who'll pay a mid-market price for that paper trail plus FSA/HSA eligibility.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs ShedRx (Shed).

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
78

Price Transparency

74
92

Nationwide Access

92
96

Formulation Options

96
84

Clinical Oversight

84
92

Contract Flexibility

76
78

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecShedRx (Shed)Breeze Meds
Cost-Efficiency Index87/10086/100
Semaglutide / mo$199/mo ($159 on a 12-month plan)$199/mo
Tirzepatide / mo$299/mo ($239 on a 12-month plan)$399/mo on the product grid; the post-intake screen shows $299 — Breeze publishes both
Semaglutide / yr (modeled)$2,388$2,388
Tirzepatide / yr (modeled)$3,588$4,788
CoverageAll 50 statesAll 50 states
Oral / sublingualYesYes
Brand-name accessYesCompounded only
Rank here#4#6

ShedRx (Shed)

87/100

Where the value is

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee

The tradeoffs

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
Visit ShedRx (Shed)

Full ShedRx (Shed) review →

Breeze Meds

86/100

Where the value is

  • Best transparency of this partner batch — NPI-verifiable named physicians (Lion MD group), named dispensing pharmacies, and LegitScript certification
  • All 50 states, with injectable semaglutide from $199/mo plus oral semaglutide (~$299) and oral tirzepatide (~$399) for the needle-averse
  • FSA/HSA eligible, which trims the effective monthly cost

The tradeoffs

  • Mid-to-higher per-month pricing — tirzepatide and the oral routes carry a premium over the cheapest all-50 rivals
  • Compounded only — not FDA-approved brand-name medication
Visit Breeze Meds

Full Breeze Meds review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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