Head-to-head · Cost-Efficiency Index
Sesame Care vs Invigor Medical
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Sesame Care
People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost.
Visit Sesame CareInvigor Medical
Value shoppers who want competitive pricing on both molecules plus a wider wellness/hormone program on one account.
Visit Invigor MedicalThe verdict
Invigor Medical takes it, leading the Cost-Efficiency Index 88 to 86. Solid mid-market cost on both molecules from an established operator — good value if you also want a broader metabolic and hormone catalog. Sesame Care still earns a B — People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Invigor Medical.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Sesame Care | Invigor Medical |
|---|---|---|
| Cost-Efficiency Index | 86/100 | 88/100 |
| Semaglutide / mo | $149/mo medication + $59/mo care subscription (that rate needs a 12-month commitment) | $225/mo (starting dose) |
| Tirzepatide / mo | Brand (Zepbound) | $350/mo (starting dose) |
| Semaglutide / yr (modeled) | — | $2,700 |
| Tirzepatide / yr (modeled) | — | $4,200 |
| Coverage | Nationwide | All 50 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #7 | #8 |
Sesame Care
86/100Where the value is
- Widest brand-name formulary we list — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and oral Rybelsus, all FDA-approved rather than compounded
- Established national marketplace operating since 2018, with LegitScript certification and BBB recognition
- Wegovy pill starts around $149/mo, and oral routes are available for the needle-averse
The tradeoffs
- Two-part cost — $149/mo medication plus a separate care subscription from $59/mo, so the all-in floor is about $208/mo, and the $59 rate itself requires a 12-month commitment
- A generalist telehealth marketplace, not a dedicated GLP-1 program
Invigor Medical
88/100Where the value is
- Competitive mid-market 'starting at' pricing on both semaglutide and tirzepatide
- Licensed in all 50 states, with a named Medical Director (Dr. Hamilton) and five named partner compounding pharmacies
- Both molecules published up front for easy cost modeling
The tradeoffs
- Both prices are floors — no dose-tier breakdown is published, so the real cost at a typical maintenance dose is unknown until intake
- The site names five partner pharmacies but never discloses which one fills a given order
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.