Head-to-head · Cost-Efficiency Index
Ryze Rx vs TRT Kingdom
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Ryze Rx
Cost-first shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.
Visit Ryze RxTRT Kingdom
Shoppers open to a TRT-focused telehealth brand's GLP-1 line who are comfortable committing to a 4-month prepay term for the advertised rate.
Visit TRT KingdomThe verdict
Ryze Rx and TRT Kingdom tie on the Cost-Efficiency Index at 54/100, so neither wins outright on the numbers. For most shoppers we'd start with Ryze Rx (ranked #364, a hair above #365) — Cost-first shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform. But TRT Kingdom is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Ryze Rx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Ryze Rx | TRT Kingdom |
|---|---|---|
| Cost-Efficiency Index | 54/100 | 54/100 |
| Semaglutide / mo | $199/mo (starting dose, 3 month plan, compounded) | $149/mo (compounded) |
| Tirzepatide / mo | $199/mo (starting dose, 3 month plan, compounded) | $199/mo (compounded) |
| Semaglutide / yr (modeled) | $2,388 | $1,788 |
| Tirzepatide / yr (modeled) | $2,388 | $2,388 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #364 | #365 |
Ryze Rx
54/100Where the value is
- Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
- Physician consultation, ongoing clinical support and discreet shipping included with each prescription
- Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
The tradeoffs
- Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
- Pharmacy partners not named - only 'US-licensed compounding pharmacies'
TRT Kingdom
54/100Where the value is
- Confirmed, real compounded GLP-1 (semaglutide) and GLP-1/GIP (tirzepatide) products exist and are separately priced, despite the company's TRT-focused branding
- Named clinical group and Chief Medical Officer (REM Health Medical Group, P.A.; Daniel Olivero) plus two named nurse practitioners
- LegitScript verification badge displayed
The tradeoffs
- The advertised $149/$199 monthly rates require committing to a 4-month plan; no month-to-month or shorter-term price is published
- Pharmacy is described only as 'an FDA registered pharmacy in the USA' -- no name, state, or accreditation given
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.