Head-to-head · Cost-Efficiency Index
Ryze Rx vs BeyondMD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Ryze Rx
Cost-first shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.
Visit Ryze RxBeyondMD
Shoppers who want a named clinical team on a broader wellness platform, not just a single-purpose GLP-1 funnel.
Visit BeyondMDThe verdict
Ryze Rx takes it, leading the Cost-Efficiency Index 54 to 53. Ryze Rx is a prescription telehealth platform for weight loss, TRT and peptide therapy, prescribing through board-certified physicians and shipping from US-licensed compounding pharmacies. BeyondMD still earns a C — Shoppers who want a named clinical team on a broader wellness platform, not just a single-purpose GLP-1 funnel.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Ryze Rx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Ryze Rx | BeyondMD |
|---|---|---|
| Cost-Efficiency Index | 54/100 | 53/100 |
| Semaglutide / mo | $199/mo (starting dose, 3 month plan, compounded) | $125/mo (starting dose, compounded) |
| Tirzepatide / mo | $199/mo (starting dose, 3 month plan, compounded) | $199/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $1,500 |
| Tirzepatide / yr (modeled) | $2,388 | $2,388 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #364 | #370 |
Ryze Rx
54/100Where the value is
- Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
- Physician consultation, ongoing clinical support and discreet shipping included with each prescription
- Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
The tradeoffs
- Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
- Pharmacy partners not named - only 'US-licensed compounding pharmacies'
BeyondMD
53/100Where the value is
- Individually named clinicians appear on the site rather than only a corporate entity: John Marley Bernard Jr., MD; Hollie Ann Hall, APRN-C; Jordan Dorsey, NP
- LegitScript-certified with the verification seal displayed
- All 50 states served per the site's own claim
The tradeoffs
- The site's own pages disagree with themselves on the tirzepatide starting price — one page says '$199,' another says '$209' — neither dated nor reconciled anywhere public
- No compounding pharmacy is named, only generic 'fully licensed U.S. 503A pharmacies' language
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.