Head-to-head · Cost-Efficiency Index
Rylo Health vs DoctorAdam
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Rylo Health
Shoppers who want one flat all-in monthly rate that doesn't rise as the dose increases.
Visit Rylo HealthDoctorAdam
Shoppers who want a needle-free oral GLP-1 with named prescribers, in the 47 states DoctorAdam actually serves.
Visit DoctorAdamThe verdict
Rylo Health takes it, leading the Cost-Efficiency Index 75 to 74. Rylo Health is a compounded GLP-1/NAD+/peptide telehealth platform operating in all 50 states through Lone Star Virtual Health PLLC and dispensing via VialsRX in Houston, TX. DoctorAdam still earns a C — Shoppers who want a needle-free oral GLP-1 with named prescribers, in the 47 states DoctorAdam actually serves.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Rylo Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Rylo Health | DoctorAdam |
|---|---|---|
| Cost-Efficiency Index | 75/100 | 74/100 |
| Semaglutide / mo | $149/mo (all doses, promotional rate, compounded) | $129/mo (starting dose, compounded oral) |
| Tirzepatide / mo | $249/mo (all doses, compounded) | $199/mo (starting dose, compounded oral) |
| Semaglutide / yr (modeled) | $1,788 | $1,548 |
| Tirzepatide / yr (modeled) | $2,988 | $2,388 |
| Coverage | All 50 states | 44 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #52 | #58 |
Rylo Health
75/100Where the value is
- Stated flat pricing regardless of dose — 'No surprise charges, no tiered pricing' — a genuine differentiator versus tiered competitors
- Medication, provider review, and shipping all stated as included in the quoted price with no add-ons found
- Names its physician group (Lone Star Virtual Health PLLC) and dispensing pharmacy (VialsRX, Houston TX) rather than leaving both anonymous
The tradeoffs
- The '$100/$160 First 20 rate' shown prominently on the homepage is limited to the first 20 signups only — most shoppers will pay the higher $149/$249 standard rate, and the promo framing can make the real price look lower than it is
- The advertised 'quarterly $349/$499' option's actual billing mechanics (one-time total vs. recurring monthly-under-commitment) could not be verified — the product pages that would clarify this render via JavaScript and returned no readable pricing text
DoctorAdam
74/100Where the value is
- Names six actual prescribers with credentials — unusually transparent for a Shopify-based storefront
- Needle-free oral tablet option for both semaglutide (from $129) and tirzepatide (from $199)
- Flat 'no hidden fees' pricing framing, with free 2-3 business day shipping
The tradeoffs
- The homepage claims 'Delivery Across All 50 States' but the site's own FAQ state list is 47 states plus DC — New Jersey, Mississippi, and Alaska are excluded
- Injectable dose-tier pricing could not be verified live in this pass (repeated 429 errors on the product pages); only the oral 'from' price is confirmed
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.