Head-to-head · Cost-Efficiency Index
Rixa Health vs Ryze Rx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Rixa Health
Patients who want the broadest medication menu (including retatrutide) and don't mind price-after-visit disclosure.
Visit Rixa HealthRyze Rx
Cost-first shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.
Visit Ryze RxThe verdict
Rixa Health and Ryze Rx tie on the Cost-Efficiency Index at 54/100, so neither wins outright on the numbers. For most shoppers we'd start with Rixa Health (ranked #363, a hair above #364) — Patients who want the broadest medication menu (including retatrutide) and don't mind price-after-visit disclosure. But Ryze Rx is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Rixa Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Rixa Health | Ryze Rx |
|---|---|---|
| Cost-Efficiency Index | 54/100 | 54/100 |
| Semaglutide / mo | Not disclosed | $199/mo (starting dose, 3 month plan, compounded) |
| Tirzepatide / mo | Not disclosed | $199/mo (starting dose, 3 month plan, compounded) |
| Semaglutide / yr (modeled) | — | $2,388 |
| Tirzepatide / yr (modeled) | — | $2,388 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #363 | #364 |
Rixa Health
54/100Where the value is
- Named medical director with stated credentials (Timothy Scott, D.O.)
- 45-state coverage, among the widest of this batch
- LegitScript certified
The tradeoffs
- Zero pricing published anywhere on the public site -- cost is disclosed only after a paid/booked visit
- No named compounding pharmacy partner
Ryze Rx
54/100Where the value is
- Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
- Physician consultation, ongoing clinical support and discreet shipping included with each prescription
- Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
The tradeoffs
- Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
- Pharmacy partners not named - only 'US-licensed compounding pharmacies'
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.