Skip to content
WeighLab

Rex MD vs Zappy Health

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Rex MD

Provider comparison

Patients seeking a Wegovy pill plan with medication and provider care in one monthly price.

Semaglutide / month
$349/moBrand Wegovy pill, all titration doses; provider care included
Tirzepatide / month
$424/moBrand Zepbound, plus a separate fee
Index 71/100 · Grade CChecked October 2026
Check Rex MD pricing Read review

Zappy Health

Provider comparison

Shoppers who want both compounded and brand GLP-1 options on one platform and are comfortable weighing a recent FDA misbranding finding.

Semaglutide / month
$249/moAll doses, month to month, compounded; $229/mo on a 3-month plan, $209/mo on 6 months, paid up front; new-user starter pack $159/mo for 3 months up front in select states
Tirzepatide / month
$349/moAll doses, month to month, compounded; $329/mo on a 3-month plan, $299/mo on 6 months, paid up front; new-user starter pack $279/mo for 3 months up front in select states
Index 70/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Zappy Health pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Rex MD has the higher Cost-Efficiency Index: 71/100 versus 70/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Rex MD
All 50 states
Zappy Health
42 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Rex MD

Zappy Health

Semaglutide / month
Rex MD: $349/moBrand Wegovy pill, all titration doses; provider care included
Zappy Health: $249/moAll doses, month to month, compounded; $229/mo on a 3-month plan, $209/mo on 6 months, paid up front; new-user starter pack $159/mo for 3 months up front in select states
Tirzepatide / month
Rex MD: $424/moBrand Zepbound, plus a separate fee
Zappy Health: $349/moAll doses, month to month, compounded; $329/mo on a 3-month plan, $299/mo on 6 months, paid up front; new-user starter pack $279/mo for 3 months up front in select states
Semaglutide / year (modeled)
Rex MD: $4,188
Zappy Health: $2,988
Tirzepatide / year (modeled)
Rex MD: $5,088
Zappy Health: $4,188
State availability
Rex MD: All 50 states
Zappy Health: 42 states
Oral / sublingual option listed
Rex MD: Yes
Zappy Health: Not listed
Brand-name access listed
Rex MD: Yes
Zappy Health: Yes
Provider facts checked
Rex MD: October 2026
Zappy Health: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Rex MD

Patients seeking a Wegovy pill plan with medication and provider care in one monthly price.

Reasons to consider it

  • Wegovy pill plan includes medication and provider care for $349 monthly
  • The pill price is locked across listed titration doses
  • Names Dr. Anthony Puopolo and the Rex MD Affiliated Medical Group

What to weigh up

  • The $349 pill plan differs from the injection route with separate program and manufacturer charges
  • Zepbound pricing depends on the prescribed dose and manufacturer terms
  • The weight program does not accept insurance
Check Rex MD pricing Read the full Rex MD review

Zappy Health

Shoppers who want both compounded and brand GLP-1 options on one platform and are comfortable weighing a recent FDA misbranding finding.

Reasons to consider it

  • Both compounded semaglutide/tirzepatide and brand Wegovy/Zepbound pathways offered on one platform
  • No insurance or membership required; the full price ladder, the same at every dose, is displayed before intake
  • LegitScript badge displayed on the site

What to weigh up

  • Does not name its dispensing pharmacy
  • No named medical director or prescriber
  • The 'as low as' $159 and $279 rates are a 3-month starter pack for new GLP-1 users, paid up front and sold only in select states; month to month is $249 and $349

Regulatory note: the FDA issued a warning letter to Kare Solutions, LLC dba Zappy in February 2026. We still list and link to Zappy Health; you should know the letter is on the public record before you decide.

Compounded drugs are not FDA-approved. Understand the medication options.

Check Zappy Health pricing Read the full Zappy Health review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Rex MDZappy Health
Normalized Cost/Month
Rex MD:
41/100
Zappy Health:
62/100
Price Transparency
Rex MD:
78/100
Zappy Health:
94/100
Nationwide Access
Rex MD:
86/100
Zappy Health:
66/100
Formulation Options
Rex MD:
90/100
Zappy Health:
79/100
Clinical Oversight
Rex MD:
89/100
Zappy Health:
55/100
Contract Flexibility
Rex MD:
55/100
Zappy Health:
61/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

Alternatives to Rex MDAlternatives to Zappy Health
More provider matchups
CoreAge Rx vs Rex MDCoreAge Rx vs Zappy Health
Choose a different comparison

Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.