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WeighLab

Primary Clinic (Direct GLP) vs NativeMed

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Primary Clinic (Direct GLP)

Provider comparison

Shoppers inside its 10 served states who want primary care bundled with the prescription and will price the membership in.

Semaglutide / month
$85/mo0.25-0.75 mg band, membership required, compounded
Tirzepatide / month
$133/mo1.25-2.5 mg band, membership required, compounded
Index 65/100 · Grade C

Compounded drugs are not FDA-approved. Understand the medication options.

Check Primary Clinic (Direct GLP) pricing Read review

NativeMed

Provider comparison

Shoppers who want one price at every dose, month to month or cheaper on a 3-month plan paid up front, without a separate membership fee.

Semaglutide / month
$179/moAll doses, monthly plan, compounded; first month $159; $149/mo on a 3-month plan paid up front
Tirzepatide / month
$259/moAll doses, monthly plan, compounded; first month $199; $183/mo on a 3-month plan paid up front
Index 65/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check NativeMed pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 65/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

Check the difference in state access

Primary Clinic (Direct GLP)
WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA
NativeMed
Coverage not published

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Primary Clinic (Direct GLP)

NativeMed

Semaglutide / month
Primary Clinic (Direct GLP): $85/mo0.25-0.75 mg band, membership required, compounded
NativeMed: $179/moAll doses, monthly plan, compounded; first month $159; $149/mo on a 3-month plan paid up front
Tirzepatide / month
Primary Clinic (Direct GLP): $133/mo1.25-2.5 mg band, membership required, compounded
NativeMed: $259/moAll doses, monthly plan, compounded; first month $199; $183/mo on a 3-month plan paid up front
Semaglutide / year (modeled)
Primary Clinic (Direct GLP): $2,088Includes $89/mo membership
NativeMed: $2,148
Tirzepatide / year (modeled)
Primary Clinic (Direct GLP): $2,664Includes $89/mo membership
NativeMed: $3,108
State availability
Primary Clinic (Direct GLP): WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA
NativeMed: Coverage not published
Oral / sublingual option listed
Primary Clinic (Direct GLP): Not listed
NativeMed: Not listed
Brand-name access listed
Primary Clinic (Direct GLP): Not confirmed
NativeMed: Not confirmed
Provider facts checked
Primary Clinic (Direct GLP): See full review
NativeMed: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Primary Clinic (Direct GLP)

Shoppers inside its 10 served states who want primary care bundled with the prescription and will price the membership in.

Reasons to consider it

  • Both molecules are priced, as dose bands, so the cost of titrating up is visible rather than hidden
  • The $89 membership buys unlimited primary care, direct text access and same-day appointments, not just a prescription
  • Real per-dose pricing rather than one headline rate

What to weigh up

  • The medication price is on top of an $89/mo membership, which the FAQ states does not include the drug — all-in is about $174/mo semaglutide and $222/mo tirzepatide
  • Prices are published as dose BANDS, and the cheapest tirzepatide band starts at 1.25 mg, below the 2.5 mg labeled starting dose
  • Only 10 states served — a coverage gamble that guts its nationwide-access score

Compounded drugs are not FDA-approved. Understand the medication options.

Check Primary Clinic (Direct GLP) pricing Read the full Primary Clinic (Direct GLP) review

NativeMed

Shoppers who want one price at every dose, month to month or cheaper on a 3-month plan paid up front, without a separate membership fee.

Reasons to consider it

  • Flat 'same price any dose' pricing removes the dose-tier price-creep common at other compounded GLP-1 sites
  • No stated membership/platform fee stacked on top of the medication price
  • Free 48-hour shipping advertised on the homepage

What to weigh up

  • The 'from $149' and 'from $183' headlines are the 3-month plan, paid up front at $447 or $549; the monthly plan costs $179 or $259
  • The first consultation is free, but a $25 fee may apply if you don't move forward on the call, and missing it or canceling within 2 hours also costs $25
  • No published list of which U.S. states NativeMed actually serves — a buyer can't confirm eligibility before starting the intake

Regulatory note: the FDA issued a warning letter to NativeMed LLC dba NativeMed in June 2026. We still list and link to NativeMed; you should know the letter is on the public record before you decide.

Compounded drugs are not FDA-approved. Understand the medication options.

Check NativeMed pricing Read the full NativeMed review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Primary Clinic (Direct GLP)NativeMed
Normalized Cost/Month
Primary Clinic (Direct GLP):
63/100
NativeMed:
74/100
Price Transparency
Primary Clinic (Direct GLP):
64/100
NativeMed:
97/100
Nationwide Access
Primary Clinic (Direct GLP):
52/100
NativeMed:
24/100
Formulation Options
Primary Clinic (Direct GLP):
66/100
NativeMed:
66/100
Clinical Oversight
Primary Clinic (Direct GLP):
74/100
NativeMed:
62/100
Contract Flexibility
Primary Clinic (Direct GLP):
80/100
NativeMed:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.