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Best-value alternatives

Alternatives to Primary Clinic (Direct GLP)

Primary Clinic (Direct GLP) scores 65/100 on our Cost-Efficiency Index (ranked #146 of 529). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.

Read the Primary Clinic (Direct GLP) review →CoreAge Rx vs Primary Clinic (Direct GLP) →
  1. Our #1 pick
    01A

    CoreAge Rx

    Ranked #1

    Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded
    Visit CoreAge Rx CoreAge Rx vs Primary Clinic (Direct GLP) →
  2. 02C

    Walgreens Weight Management

    Ranked #145

    Walgreens Weight Management is a self-pay virtual-care add-on launched February 26, 2026, connecting eligible adults (18-64) in 29 states with licensed clinicians for a $49-per-visit consultation.

    Sema
    $199/mo (0.25 mg dose, brand-name)
    Tirz
    Not disclosed
    Coverage
    All 50 states
    Brand
    Yes
    Visit Walgreens Weight Management Walgreens Weight Management vs Primary Clinic (Direct GLP) →
  3. 03C

    VirtualCare2Go

    Ranked #144

    VirtualCare2Go is a Texas-area (Dallas/Fort Worth) telehealth practice offering weight- loss injections, oral tablets, and a lower-cost compounded semaglutide track.

    Sema
    $279/mo (bundle, compounded)
    Tirz
    $629/mo (bundle, compounded)
    Coverage
    All 50 states
    Brand
    Compounded
    Visit VirtualCare2Go VirtualCare2Go vs Primary Clinic (Direct GLP) →
  4. 04C

    Tyde Wellness

    Ranked #143

    Tyde Wellness is a compounded-GLP-1 and longevity telehealth platform (weight loss, HRT, hair, longevity) serving all 50 states, with semaglutide starting at $149/mo and tirzepatide at $249/mo.

    Sema
    $149/mo (microdose tier, starting dose, compounded)
    Tirz
    $249/mo (microdose tier, starting dose, compounded)
    Coverage
    All 50 states
    Brand
    Compounded
    Visit Tyde Wellness Tyde Wellness vs Primary Clinic (Direct GLP) →
  5. 05C

    TrueMe

    Ranked #142

    TrueMe is a cash-pay telehealth brand offering compounded semaglutide and tirzepatide with added B vitamins, alongside NAD+, sermorelin and glutathione.

    Sema
    $159/mo (compounded)
    Tirz
    $189/mo (compounded)
    Coverage
    6 states
    Brand
    Yes
    Visit TrueMe TrueMe vs Primary Clinic (Direct GLP) →
  6. 06C

    TD Tele-Doc Weight Loss

    Ranked #141

    TD Tele-Doc (teledocweightloss.com) is a small, Richmond, VA-based virtual weight-loss clinic offering semaglutide 'starting at $145' -- but that price is quoted within an insurance/Medicare-billing model rather than as a flat cash rate.

    Sema
    $145/mo (compounded)
    Tirz
    Not disclosed
    Coverage
    2 states
    Brand
    Yes
    Visit TD Tele-Doc Weight Loss TD Tele-Doc Weight Loss vs Primary Clinic (Direct GLP) →
  7. 07C

    Rewinding RX

    Ranked #140

    Rewinding RX (Rewinding RX Ltd.) is a longevity-framed telehealth platform selling FOUR distinct GLP-1 products: standard-dose semaglutide ($139/mo) and tirzepatide ($189/mo).

    Sema
    $139/mo (microdose tier, compounded)
    Tirz
    $189/mo (microdose tier, compounded)
    Coverage
    All 50 states
    Brand
    Compounded
    Visit Rewinding RX Rewinding RX vs Primary Clinic (Direct GLP) →
  8. 08C

    NuvaHealth

    Ranked #139

    NuvaHealth is a compounded GLP-1 telehealth platform serving all 50 states, dispensing through four named pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma Rx) and LegitScript certified.

    Sema
    $89/mo (starting dose, first-month rate, compounded)
    Tirz
    $139/mo (starting dose, first-month rate, compounded)
    Coverage
    Multi-state
    Brand
    Compounded
    Visit NuvaHealth NuvaHealth vs Primary Clinic (Direct GLP) →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

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