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WeighLab

PlexusDx vs Amble

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

PlexusDx

Provider comparison

Shoppers who want one price at every dose, an oral option for either molecule, and all 50 states.

Semaglutide / month
$189/moSame price at every dose, month to month, compounded, all-inclusive; $169/mo on a 3-month plan, $149/mo on a 6-month plan
Tirzepatide / month
$289/moSame price at every dose, month to month, compounded, all-inclusive; $269/mo on a 3-month plan, $249/mo on a 6-month plan
Index 79/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check PlexusDx pricing Read review

Amble

Provider comparison

Cost-first shoppers who want a single flat rate across semaglutide and tirzepatide, if a 3- or 6-month prepay is acceptable.

Semaglutide / month
$179/moAll doses, compounded
Tirzepatide / month
$179/moAll doses, compounded
Index 78/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Amble pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

PlexusDx has the higher Cost-Efficiency Index: 79/100 versus 78/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

PlexusDx

Amble

Semaglutide / month
PlexusDx: $189/moSame price at every dose, month to month, compounded, all-inclusive; $169/mo on a 3-month plan, $149/mo on a 6-month plan
Amble: $179/moAll doses, compounded
Tirzepatide / month
PlexusDx: $289/moSame price at every dose, month to month, compounded, all-inclusive; $269/mo on a 3-month plan, $249/mo on a 6-month plan
Amble: $179/moAll doses, compounded
Semaglutide / year (modeled)
PlexusDx: $2,268
Amble: $2,148
Tirzepatide / year (modeled)
PlexusDx: $3,468
Amble: $2,148
State availability
PlexusDx: All 50 states
Amble: All 50 states
Oral / sublingual option listed
PlexusDx: Yes
Amble: Not listed
Brand-name access listed
PlexusDx: Not confirmed
Amble: Not confirmed
Provider facts checked
PlexusDx: October 2026
Amble: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

PlexusDx

Shoppers who want one price at every dose, an oral option for either molecule, and all 50 states.

Reasons to consider it

  • LegitScript Certified, with the seal on the homepage
  • Same price at every dose, with no membership: semaglutide $189 and tirzepatide $289 month to month, less on 3- and 6-month plans
  • Both molecules come as weekly injections or daily tablets

What to weigh up

  • The 'starts at' $149 and $249 figures are 6-month-plan prices; month to month, semaglutide is $189 and tirzepatide $289
  • The tablets cost more than the shots: oral semaglutide starts at $249/mo and oral tirzepatide at $279/mo on the 6-month plan
  • No named prescriber, medical director, or specific compounding pharmacy

Compounded drugs are not FDA-approved. Understand the medication options.

Check PlexusDx pricing Read the full PlexusDx review

Amble

Cost-first shoppers who want a single flat rate across semaglutide and tirzepatide, if a 3- or 6-month prepay is acceptable.

Reasons to consider it

  • One price at every dose: $179 month to month, $160 a month on a 3-month plan, $135 on a 6-month plan
  • True no-commitment option exists ($179/mo, pay as you go) alongside the prepay plans
  • All 50 states, with only 5 requiring a live video visit instead of async intake

What to weigh up

  • The advertised low-end price ($135-$160/mo) is not a monthly bill — the whole 3- or 6-month plan is charged at purchase and can't be refunded once medication ships
  • Amble says 'all 50 states (exclusions apply)' but doesn't list the exclusions
  • Amble sells 'compounded GLP-1' without naming semaglutide or tirzepatide, so ask which one you'd be prescribed

Compounded drugs are not FDA-approved. Understand the medication options.

Check Amble pricing Read the full Amble review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

PlexusDxAmble
Normalized Cost/Month
PlexusDx:
76/100
Amble:
75/100
Price Transparency
PlexusDx:
94/100
Amble:
94/100
Nationwide Access
PlexusDx:
86/100
Amble:
86/100
Formulation Options
PlexusDx:
77/100
Amble:
66/100
Clinical Oversight
PlexusDx:
74/100
Amble:
79/100
Contract Flexibility
PlexusDx:
55/100
Amble:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.