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WeighLab

Peptivo vs Nucific

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Peptivo

Provider comparison

Shoppers who value verifiable named pharmacy and medical-leadership credentials, willing to complete an intake quiz to see final pricing.

Semaglutide / month
$179/moCompounded medication, consultation, shipping and support included
Tirzepatide / month
$279/moCompounded medication, consultation, shipping and support included
Index 66/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Peptivo pricing Read review

Nucific

Provider comparison

Shoppers who want low advertised prices on compounded semaglutide or tirzepatide, with medication, labs and provider visits in one price and no membership fee.

Semaglutide / month
$117/moLowest advertised price; plan length and dose not stated, compounded
Tirzepatide / month
$139/moLowest advertised price; plan length and dose not stated, compounded
Index 66/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Nucific pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 66/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Peptivo

Nucific

Semaglutide / month
Peptivo: $179/moCompounded medication, consultation, shipping and support included
Nucific: $117/moLowest advertised price; plan length and dose not stated, compounded
Tirzepatide / month
Peptivo: $279/moCompounded medication, consultation, shipping and support included
Nucific: $139/moLowest advertised price; plan length and dose not stated, compounded
Semaglutide / year (modeled)
Peptivo: $2,148
Nucific: $1,404
Tirzepatide / year (modeled)
Peptivo: $3,348
Nucific: $1,668
State availability
Peptivo: Coverage not published
Nucific: Coverage not published
Oral / sublingual option listed
Peptivo: Not listed
Nucific: Not listed
Brand-name access listed
Peptivo: Yes
Nucific: Yes
Provider facts checked
Peptivo: October 2026
Nucific: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Peptivo

Shoppers who value verifiable named pharmacy and medical-leadership credentials, willing to complete an intake quiz to see final pricing.

Reasons to consider it

  • Four named, verifiable compounding pharmacy partners across multiple states
  • Named Chief Medical Innovation Officer (MD) and VP of Pharmacy Operations, plus a physician advisory board
  • Ships to all 50 states

What to weigh up

  • Its ads quote daily rates and 90-day bundles; confirm your plan length and total before paying
  • The terms limit refunds to medical disqualification or billing error, despite broader money-back language in ads
  • Ask what dose and medication any add-on weight-loss product contains

Compounded drugs are not FDA-approved. Understand the medication options.

Check Peptivo pricing Read the full Peptivo review

Nucific

Shoppers who want low advertised prices on compounded semaglutide or tirzepatide, with medication, labs and provider visits in one price and no membership fee.

Reasons to consider it

  • Publishes prices up front: compounded semaglutide from $117 a month and tirzepatide from $139, plus lower-dose microdose plans and brand-name Ozempic and Zepbound
  • The treatment price includes the medication, required labs and provider consultations, with no membership fee
  • Prescribing is done by OpenLoop Health's network of U.S.-licensed providers

What to weigh up

  • The 'as low as' prices don't say which plan length or dose they belong to, and the sign-up discount applies to the first payment only
  • Fees aren't refunded if you cancel mid-cycle, and you must cancel at least 72 hours before your next billing date
  • Doesn't name its pharmacies or list the states it serves; its founder, Dr. Amy Lee, MD, is named, but no medical director for the prescribing network is

Compounded drugs are not FDA-approved. Understand the medication options.

Check Nucific pricing Read the full Nucific review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

PeptivoNucific
Normalized Cost/Month
Peptivo:
73/100
Nucific:
80/100
Price Transparency
Peptivo:
86/100
Nucific:
78/100
Nationwide Access
Peptivo:
24/100
Nucific:
24/100
Formulation Options
Peptivo:
79/100
Nucific:
79/100
Clinical Oversight
Peptivo:
77/100
Nucific:
76/100
Contract Flexibility
Peptivo:
55/100
Nucific:
53/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.