Pepti vs Synergy Rx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Pepti

Provider comparison

Shoppers who want to see the price of every dose step before they start, with no membership fee on top.

Semaglutide / month: $99/mo0.25 mg starting dose, compounded; $109–$199 at higher doses
Tirzepatide / month: $159/mo2.5 mg starting dose, compounded; $179–$319 at higher doses

Index 80/100 · Grade B−Checked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Pepti pricing Read review

Synergy Rx

Provider comparison

Readers comparing injection, dissolving-tablet and brand-name routes who will confirm the plan total and billing schedule.

Semaglutide / month: $199Starting price (compounded injection; billing cycle and dose not stated)
Tirzepatide / month: $349Starting price (compounded injection; billing cycle and dose not stated)

Index 79/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Synergy Rx pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Pepti has the higher Cost-Efficiency Index: 80/100 versus 79/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Pepti: All 50 states
Synergy Rx: All 50 states claimed in FAQ; subject to provider availability

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Pepti

Synergy Rx

Semaglutide / month: Pepti: $99/mo0.25 mg starting dose, compounded; $109–$199 at higher doses; Synergy Rx: $199Starting price (compounded injection; billing cycle and dose not stated)

Tirzepatide / month: Pepti: $159/mo2.5 mg starting dose, compounded; $179–$319 at higher doses; Synergy Rx: $349Starting price (compounded injection; billing cycle and dose not stated)

Semaglutide / year (modeled): Pepti: $1,28713 charges; Synergy Rx: $2,388

Tirzepatide / year (modeled): Pepti: $2,06713 charges; Synergy Rx: $4,188

State availability: Pepti: All 50 states; Synergy Rx: All 50 states claimed in FAQ; subject to provider availability

Oral / sublingual option listed: Pepti: Not listed; Synergy Rx: Yes

Brand-name access listed: Pepti: Not confirmed; Synergy Rx: Yes

Provider facts checked: Pepti: October 2026; Synergy Rx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Pepti

Shoppers who want to see the price of every dose step before they start, with no membership fee on top.

Reasons to consider it

Every dose has its own published price: semaglutide runs $99 to $199 and tirzepatide $159 to $319
No membership fee; the medication price includes physician review, dose adjustments and free shipping
Names a reviewing physician and a dispensing pharmacy, Olympia Pharmacy

What to weigh up

The price rises as your dose goes up, so the $99 starting figure covers only the first step of semaglutide
It bills every 28 days rather than monthly, which adds up to 13 charges a year
You pay at checkout before a provider reviews your intake; you're refunded if you're declined

Compounded drugs are not FDA-approved. Understand the medication options.

Check Pepti pricing Read the full Pepti review

Synergy Rx

Readers comparing injection, dissolving-tablet and brand-name routes who will confirm the plan total and billing schedule.

Reasons to consider it

Offers compounded injections, compounded oral dissolving tablets and brand-name Wegovy, Mounjaro and Ozempic
Lists starting prices before consultation
FAQ says all 50 states, subject to state rules and licensed-provider availability

What to weigh up

Starting figures do not specify the billing cycle or dose; confirm the complete plan total
Oral semaglutide starts at $299 and oral tirzepatide at $399, above the injection floors
State availability is conditional; confirm that a licensed provider can treat you

Compounded drugs are not FDA-approved. Understand the medication options.

Check Synergy Rx pricing Read the full Synergy Rx review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

PeptiSynergy Rx

Normalized Cost/Month: Pepti:
81/100; Synergy Rx:
74/100

Price Transparency: Pepti:
84/100; Synergy Rx:
65/100

Nationwide Access: Pepti:
86/100; Synergy Rx:
88/100

Formulation Options: Pepti:
66/100; Synergy Rx:
95/100

Clinical Oversight: Pepti:
86/100; Synergy Rx:
90/100

Contract Flexibility: Pepti:
67/100; Synergy Rx:
68/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.