Pallas Health vs Rylo Health

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Pallas Health

Provider comparison

Shoppers who want the whole cost stated before signup, one price at every dose, and the option of a brand-name drug or a tablet on the same account.

Semaglutide / month: $199Every 4 weeks (same price at every dose, compounded, care included; first month $139; $139/mo average on the annual plan)
Tirzepatide / month: $299Every 4 weeks (same price at every dose, compounded, care included; first month $179; $239/mo average on the annual plan)

Index 85/100 · Grade BChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Pallas Health pricing Read review

Rylo Health

Provider comparison

Shoppers who want one flat all-in monthly rate that doesn't rise as the dose increases.

Semaglutide / month: $139/moAll doses, monthly plan; lower rates with quarterly prepayment, compounded
Tirzepatide / month: $229/moAll doses, monthly plan; lower rates with quarterly prepayment, compounded

Index 84/100 · Grade BChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Rylo Health pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Pallas Health has the higher Cost-Efficiency Index: 85/100 versus 84/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Pallas Health: All 50 states + DC
Rylo Health: All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Pallas Health

Rylo Health

Semaglutide / month: Pallas Health: $199Every 4 weeks (same price at every dose, compounded, care included; first month $139; $139/mo average on the annual plan); Rylo Health: $139/moAll doses, monthly plan; lower rates with quarterly prepayment, compounded

Tirzepatide / month: Pallas Health: $299Every 4 weeks (same price at every dose, compounded, care included; first month $179; $239/mo average on the annual plan); Rylo Health: $229/moAll doses, monthly plan; lower rates with quarterly prepayment, compounded

Semaglutide / year (modeled): Pallas Health: $2,58713 charges; Rylo Health: $1,668

Tirzepatide / year (modeled): Pallas Health: $3,88713 charges; Rylo Health: $2,748

State availability: Pallas Health: All 50 states + DC; Rylo Health: All 50 states

Oral / sublingual option listed: Pallas Health: Yes; Rylo Health: Not listed

Brand-name access listed: Pallas Health: Yes; Rylo Health: Not confirmed

Provider facts checked: Pallas Health: October 2026; Rylo Health: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Pallas Health

Shoppers who want the whole cost stated before signup, one price at every dose, and the option of a brand-name drug or a tablet on the same account.

Reasons to consider it

Both molecules are priced publicly and stay the same at every dose: $199 or $299 every 4 weeks after a $139 or $179 first month
The annual plan brings the average down to $139 a month for semaglutide and $239 for tirzepatide
Brand-name Wegovy (pen or pill), Foundayo, Zepbound, Ozempic and Mounjaro are sold cash-pay, and compounded semaglutide also comes as a daily tablet

What to weigh up

Billing every 4 weeks is 13 charges a year, not 12, so a year costs more than 12 times the figure
Brand-name drugs are full cash-pay prices ($1,069 to $1,349 a month) with no insurance routing
Once a prescription is issued, that cycle's order is final and isn't prorated

Compounded drugs are not FDA-approved. Understand the medication options.

Check Pallas Health pricing Read the full Pallas Health review

Rylo Health

Shoppers who want one flat all-in monthly rate that doesn't rise as the dose increases.

Reasons to consider it

Stated flat pricing regardless of dose — 'No surprise charges, no tiered pricing' — a genuine differentiator versus tiered competitors
Medication, provider review and shipping are all stated as included in the quoted price, with no add-ons listed
Names its physician group (Lone Star Virtual Health PLLC) and dispensing pharmacy (VialsRX, Houston TX) rather than leaving both anonymous

What to weigh up

The advertised $100/$160 monthly equivalents require $299/$479 paid once per quarter
Its product pages say no membership fees, while the terms describe separately billed membership; confirm the complete charge
The terms say refunds depend on the treatment stage and describe the full terms as still being finalized

Compounded drugs are not FDA-approved. Understand the medication options.

Check Rylo Health pricing Read the full Rylo Health review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Pallas HealthRylo Health

Normalized Cost/Month: Pallas Health:
77/100; Rylo Health:
87/100

Price Transparency: Pallas Health:
94/100; Rylo Health:
94/100

Nationwide Access: Pallas Health:
86/100; Rylo Health:
86/100

Formulation Options: Pallas Health:
95/100; Rylo Health:
66/100

Clinical Oversight: Pallas Health:
74/100; Rylo Health:
83/100

Contract Flexibility: Pallas Health:
83/100; Rylo Health:
83/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.