Head-to-head · Cost-Efficiency Index
Open Water Rx vs T2D.com
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Open Water Rx
Cost-first shoppers who want all-inclusive compounded GLP-1 pricing from four named 503A pharmacies, if you qualify for the promo codes.
Visit Open Water RxT2D.com
Shoppers who already have a semaglutide prescription from an outside provider and just want a cheap fill-and-ship pharmacy.
Visit T2D.comThe verdict
Open Water Rx and T2D.com tie on the Cost-Efficiency Index at 53/100, so neither wins outright on the numbers. For most shoppers we'd start with Open Water Rx (ranked #379, a hair above #382) — Cost-first shoppers who want all-inclusive compounded GLP-1 pricing from four named 503A pharmacies, if you qualify for the promo codes. But T2D.com is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Open Water Rx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Open Water Rx | T2D.com |
|---|---|---|
| Cost-Efficiency Index | 53/100 | 53/100 |
| Semaglutide / mo | $199/mo (promotional rate, plus a separate fee, compounded) | $99/mo (0.25 mg dose, compounded) |
| Tirzepatide / mo | $339/mo (compounded) | Not disclosed |
| Semaglutide / yr (modeled) | $2,388 | $1,188 |
| Tirzepatide / yr (modeled) | $4,068 | — |
| Coverage | Coverage not published | 1 state |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #379 | #382 |
Open Water Rx
53/100Where the value is
- Names four specific 503A compounding pharmacies (RedRock, HealthWarehouse, Precision Compounding, Triad Rx) — most competitors disclose zero
- Pricing is genuinely all-inclusive — clinician review, medication, and shipping bundled with no separate visit fee
- LegitScript certification seals displayed
The tradeoffs
- The lower, more prominent $159/$219 figures depend on promo codes (SEMASUMMER, FOUNDER) stacked on top of stated $199/$339 standing prices — unclear whether these codes are permanent
- A '12-Week Plan' at $169/month strongly implies a multi-month prepay requirement, but the page never states the actual upfront total
T2D.com
53/100Where the value is
- $170/mo all-inclusive full-service price (prescriber + medication) is meaningfully below many compounded-GLP-1 competitors
- $99/mo BYOP option is a genuine discount for patients who already hold a valid outside prescription
- No-contract, cancel-anytime billing stated explicitly on the pricing page
The tradeoffs
- No published tirzepatide price anywhere on the site despite tirzepatide being advertised — pricing parity with semaglutide is assumed, not confirmed
- State availability is not disclosed anywhere on the public site — impossible to confirm eligibility pre-signup
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.