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WeighLab

Open Water Rx vs PreventiveMD

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Open Water Rx

Provider comparison

Shoppers who want published monthly all-dose injection prices and separate oral options.

Semaglutide / month
$169/moAll doses, monthly compounded injection program
Tirzepatide / month
$219/moAll doses, monthly compounded injection program
Index 78/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Open Water Rx pricing Read review

PreventiveMD

Provider comparison

Cost-first shoppers who want compounded GLP-1s from $83/mo all-in, with brand upgrade paths.

Semaglutide / month
$83/moAs low as, term not published, all-in, compounded
Tirzepatide / month
$97/moAs low as, term not published, all-in, compounded
Index 77/100 · Grade CChecked August 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check PreventiveMD pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Open Water Rx has the higher Cost-Efficiency Index: 78/100 versus 77/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Open Water Rx
All 50 states
PreventiveMD
36 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Open Water Rx

PreventiveMD

Semaglutide / month
Open Water Rx: $169/moAll doses, monthly compounded injection program
PreventiveMD: $83/moAs low as, term not published, all-in, compounded
Tirzepatide / month
Open Water Rx: $219/moAll doses, monthly compounded injection program
PreventiveMD: $97/moAs low as, term not published, all-in, compounded
Semaglutide / year (modeled)
Open Water Rx: $2,028
PreventiveMD: $996
Tirzepatide / year (modeled)
Open Water Rx: $2,628
PreventiveMD: $1,164
State availability
Open Water Rx: All 50 states
PreventiveMD: 36 states
Oral / sublingual option listed
Open Water Rx: Yes
PreventiveMD: Not listed
Brand-name access listed
Open Water Rx: Not confirmed
PreventiveMD: Yes
Provider facts checked
Open Water Rx: October 2026
PreventiveMD: August 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Open Water Rx

Shoppers who want published monthly all-dose injection prices and separate oral options.

Reasons to consider it

  • One-month injection plans have no dose-based price increase
  • Clinical review, medication if prescribed, shipping and follow-up are included
  • Oral semaglutide and tirzepatide have separate published prices

What to weigh up

  • Multi-month plans require prepayment; confirm the total before buying
  • Cancel at least 72 hours before the next billing date
  • The homepage says no charge before approval, while its cancellation policy describes payment at checkout and a refund if declined

Compounded drugs are not FDA-approved. Understand the medication options.

Check Open Water Rx pricing Read the full Open Water Rx review

PreventiveMD

Cost-first shoppers who want compounded GLP-1s from $83/mo all-in, with brand upgrade paths.

Reasons to consider it

  • Compounded semaglutide from $83/mo and tirzepatide from $97/mo, billed as one all-in monthly price
  • Brand Wegovy, Zepbound, and Foundayo (oral GLP-1) available on the same platform
  • US-licensed provider reviews requests within 24 hours — no video visit required

What to weigh up

  • Both figures are 'as low as' rates and the qualifying term is not published anywhere — the checkout is gated, so whether $97 is month-to-month or a multi-month prepay cannot be established before signing up
  • Brand-name routes are priced separately and do carry a fee: $49/mo membership plus medication from $149/mo for Foundayo and Wegovy, from $299/mo for Zepbound
  • No state count is published, and a state-variant waitlist implies some states are unserved

Compounded drugs are not FDA-approved. Understand the medication options.

Check PreventiveMD pricing Read the full PreventiveMD review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Open Water RxPreventiveMD
Normalized Cost/Month
Open Water Rx:
81/100
PreventiveMD:
87/100
Price Transparency
Open Water Rx:
94/100
PreventiveMD:
78/100
Nationwide Access
Open Water Rx:
86/100
PreventiveMD:
66/100
Formulation Options
Open Water Rx:
77/100
PreventiveMD:
84/100
Clinical Oversight
Open Water Rx:
59/100
PreventiveMD:
82/100
Contract Flexibility
Open Water Rx:
55/100
PreventiveMD:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.