Head-to-head · Cost-Efficiency Index
Onyx Weight Loss vs ElixaMD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Onyx Weight Loss
Patients located in one of Onyx's 8 served states who want a boutique, NP-led clinic bundling weight loss with hormone and peptide care.
Visit Onyx Weight LossElixaMD
Shoppers who also want skincare/hair-loss/men's-health services bundled with GLP-1 care.
Visit ElixaMDThe verdict
Onyx Weight Loss takes it, leading the Cost-Efficiency Index 51 to 50. Onyx Weight Loss is a small, nurse-practitioner-founded telehealth clinic (no MD medical director identified) serving 8 named states, offering GLP-1 and GLP-1/GIP medications alongside HRT and peptide therapy. ElixaMD still earns a C — Shoppers who also want skincare/hair-loss/men's-health services bundled with GLP-1 care.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Onyx Weight Loss.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Onyx Weight Loss | ElixaMD |
|---|---|---|
| Cost-Efficiency Index | 51/100 | 50/100 |
| Semaglutide / mo | Not disclosed | Not disclosed |
| Tirzepatide / mo | Not disclosed | Not disclosed |
| Semaglutide / yr (modeled) | — | — |
| Tirzepatide / yr (modeled) | — | — |
| Coverage | 8 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #402 | #408 |
Onyx Weight Loss
51/100Where the value is
- Clear, specific 8-state service list published
- Bundles weight loss with hormone replacement and peptide therapy under one clinic
- Small team with named founders and identifiable clinical staff
The tradeoffs
- No pricing published anywhere on the public site
- No physician/MD medical director -- leadership is NP/RN-only
ElixaMD
50/100Where the value is
- Three named, specific compounding pharmacy partners (unusually transparent)
- Backed by an established multi-state physician network (OpenLoop Health)
- Bundles multiple telehealth verticals beyond just weight loss
The tradeoffs
- No verifiable pricing anywhere -- both /glp-1 and /pricing pages 404'd
- No single named medical director, just a network reference
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.