Head-to-head · Cost-Efficiency Index
Nurx vs MyStart Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Nurx
Shoppers who specifically want FDA-approved brand-name Wegovy/Zepbound access through an established telehealth brand and don't want a compounded product.
Visit NurxMyStart Health
Shoppers who want a single flat all-inclusive monthly price and don't need semaglutide vs. tirzepatide broken out separately.
Visit MyStart HealthThe verdict
Nurx takes it, leading the Cost-Efficiency Index 50 to 49. Nurx, a Thirty Madison company, is an established telehealth brand that connects patients to prescriptions for brand-name GLP-1s (Wegovy, Zepbound, Ozempic, Mounjaro, Saxenda, Victoza) filled at the patient's own local pharmacy. MyStart Health still earns a C — Shoppers who want a single flat all-inclusive monthly price and don't need semaglutide vs. tirzepatide broken out separately.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Nurx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Nurx | MyStart Health |
|---|---|---|
| Cost-Efficiency Index | 50/100 | 49/100 |
| Semaglutide / mo | $1,379/mo (brand Wegovy) | $299/mo (compounded) |
| Tirzepatide / mo | $1,079/mo (brand Zepbound) | Not disclosed |
| Semaglutide / yr (modeled) | $16,548 | $3,588 |
| Tirzepatide / yr (modeled) | $12,948 | — |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #411 | #418 |
Nurx
50/100Where the value is
- Backed by Thirty Madison, an established telehealth parent company that also runs Keeps and Cove
- Prescribes genuinely FDA-approved brand-name GLP-1s (Wegovy, Zepbound, Ozempic, Mounjaro, Saxenda, Victoza) rather than a compounded substitute
- Names two Medical Directors on its team page (Dr. Peter Young, Dr. Neil Zlatniski)
The tradeoffs
- Sells NO compounded semaglutide or tirzepatide at any price — a prior dataset's '$179/mo compounded' figure does not describe any product actually on this site
- Nurx's own advertised medication prices ($1,000-$1,300/mo) are Nurx's estimate of what the PHARMACY will charge, not a price Nurx guarantees or collects — actual cost varies by pharmacy and insurance
MyStart Health
49/100Where the value is
- Genuinely all-inclusive stated price: physician evaluations, unlimited follow-ups, bloodwork, and shipping are explicitly bundled into the $299 figure with 'no hidden fees'
- Price-lock guarantee explicitly covers dose increases — the FAQ states the price won't rise 'even if your dosage increases'
- Named Chief Medical Advisor (Dr. Ritu Chopra, Beverly Hills MD)
The tradeoffs
- Does not publish separate pricing for semaglutide vs. tirzepatide — $299 is a single blended program price, so it's unclear which drug (or whether both) that figure actually buys
- A sitewide 'Lifetime 25% Off' promo banner is not reconciled against the stated '$299/month excluding any discounts' base price or the price-lock guarantee's 'excluding our first-time discount' exception — genuinely ambiguous what a patient ends up paying long-term
Regulatory note: the FDA issued a warning letter to Matthew Stern, CEO MyStart Health LLC. in September 2025. We still list and link to MyStart Health; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.