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WeighLab

NP2GO vs PlexusDx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

NP2GO

Provider comparison

Patients who want nurse-practitioner-led consultations and prefer comparing a monthly program against paying for medication and visits separately.

Semaglutide / month
$199/moMonths 1–3 on monthly program; then $299
Tirzepatide / month
$299/moMonths 1–3 on monthly program; then $399
Index 80/100 · Grade B−Checked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check NP2GO pricing Read review

PlexusDx

Provider comparison

Shoppers who want one price at every dose, an oral option for either molecule, and all 50 states.

Semaglutide / month
$189/moSame price at every dose, month to month, compounded, all-inclusive; $169/mo on a 3-month plan, $149/mo on a 6-month plan
Tirzepatide / month
$289/moSame price at every dose, month to month, compounded, all-inclusive; $269/mo on a 3-month plan, $249/mo on a 6-month plan
Index 79/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check PlexusDx pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

NP2GO has the higher Cost-Efficiency Index: 80/100 versus 79/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

NP2GO
Claims 40 states; confirm eligibility
PlexusDx
All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

NP2GO

PlexusDx

Semaglutide / month
NP2GO: $199/moMonths 1–3 on monthly program; then $299
PlexusDx: $189/moSame price at every dose, month to month, compounded, all-inclusive; $169/mo on a 3-month plan, $149/mo on a 6-month plan
Tirzepatide / month
NP2GO: $299/moMonths 1–3 on monthly program; then $399
PlexusDx: $289/moSame price at every dose, month to month, compounded, all-inclusive; $269/mo on a 3-month plan, $249/mo on a 6-month plan
Semaglutide / year (modeled)
NP2GO: $2,388
PlexusDx: $2,268
Tirzepatide / year (modeled)
NP2GO: $3,588
PlexusDx: $3,468
State availability
NP2GO: Claims 40 states; confirm eligibility
PlexusDx: All 50 states
Oral / sublingual option listed
NP2GO: Not listed
PlexusDx: Yes
Brand-name access listed
NP2GO: Yes
PlexusDx: Not confirmed
Provider facts checked
NP2GO: October 2026
PlexusDx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

NP2GO

Patients who want nurse-practitioner-led consultations and prefer comparing a monthly program against paying for medication and visits separately.

Reasons to consider it

  • Names founder Kara De La Peña, APRN-CNP, and its clinical team
  • Publishes dose-level prices for both medications and both payment options
  • Monthly program includes provider check-ins without a separate visit fee

What to weigh up

  • Monthly semaglutide rises from $199 to $299 after month three; tirzepatide rises from $299 to $399
  • Pay As You Go medication starts at $150/$250, rises with dose and adds a $99 provider visit every three months
  • Homepage coverage counts vary; confirm your state before booking

Compounded drugs are not FDA-approved. Understand the medication options.

Check NP2GO pricing Read the full NP2GO review

PlexusDx

Shoppers who want one price at every dose, an oral option for either molecule, and all 50 states.

Reasons to consider it

  • LegitScript Certified, with the seal on the homepage
  • Same price at every dose, with no membership: semaglutide $189 and tirzepatide $289 month to month, less on 3- and 6-month plans
  • Both molecules come as weekly injections or daily tablets

What to weigh up

  • The 'starts at' $149 and $249 figures are 6-month-plan prices; month to month, semaglutide is $189 and tirzepatide $289
  • The tablets cost more than the shots: oral semaglutide starts at $249/mo and oral tirzepatide at $279/mo on the 6-month plan
  • No named prescriber, medical director, or specific compounding pharmacy

Compounded drugs are not FDA-approved. Understand the medication options.

Check PlexusDx pricing Read the full PlexusDx review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

NP2GOPlexusDx
Normalized Cost/Month
NP2GO:
71/100
PlexusDx:
76/100
Price Transparency
NP2GO:
88/100
PlexusDx:
94/100
Nationwide Access
NP2GO:
80/100
PlexusDx:
86/100
Formulation Options
NP2GO:
85/100
PlexusDx:
77/100
Clinical Oversight
NP2GO:
82/100
PlexusDx:
74/100
Contract Flexibility
NP2GO:
80/100
PlexusDx:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.