Nolu vs Enhance MD

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Nolu

Provider comparison

Shoppers who want GLP-1 plus an adjacent microdose or NAD+/longevity line without juggling separate accounts.

Semaglutide / month: $199Every 4 weeks (same price at every dose, compounded, consultation and shipping included; less per cycle on longer plans, down to $137)
Tirzepatide / month: $279Every 4 weeks (same price at every dose, compounded, consultation and shipping included; less per cycle on longer plans)

Index 79/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Nolu pricing Read review

Enhance MD

Affiliate partner

Shoppers who want flat pricing that doesn't rise with the dose, routine lab monitoring and a semaglutide-plus-tirzepatide combo option, and who don't need a brand-name or oral route.

Semaglutide / month: $212/moFirst month $112
Tirzepatide / month: $280/moFirst month $180

Index 76/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Enhance MD pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Nolu has the higher Cost-Efficiency Index: 79/100 versus 76/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Nolu: All 50 states + Washington, D.C. (standard eligibility hedge)
Enhance MD: 40 states + DC

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Nolu

Enhance MD

Semaglutide / month: Nolu: $199Every 4 weeks (same price at every dose, compounded, consultation and shipping included; less per cycle on longer plans, down to $137); Enhance MD: $212/moFirst month $112

Tirzepatide / month: Nolu: $279Every 4 weeks (same price at every dose, compounded, consultation and shipping included; less per cycle on longer plans); Enhance MD: $280/moFirst month $180

Semaglutide / year (modeled): Nolu: $2,58713 charges; Enhance MD: $2,544

Tirzepatide / year (modeled): Nolu: $3,62713 charges; Enhance MD: $3,360

State availability: Nolu: All 50 states + Washington, D.C. (standard eligibility hedge); Enhance MD: 40 states + DC

Oral / sublingual option listed: Nolu: Yes; Enhance MD: Not listed

Brand-name access listed: Nolu: Not confirmed; Enhance MD: Not confirmed

Provider facts checked: Nolu: October 2026; Enhance MD: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Nolu

Shoppers who want GLP-1 plus an adjacent microdose or NAD+/longevity line without juggling separate accounts.

Reasons to consider it

Both molecules published up front at one price for every dose: $199 semaglutide and $279 tirzepatide every 4 weeks, plus oral semaglutide at $239
All-inclusive per-cycle pricing: consultation, medication and shipping bundled, no separate membership fee
Longer plans lower the cost of each 4-week cycle, down to $137

What to weigh up

Billed every 4 weeks, not per calendar month — 13 charges a year, not 12, so the real annualized cost runs ~8% above the headline figure
No named medical director, prescriber, or compounding pharmacy disclosed anywhere on the site
The longer plans' lengths and per-plan totals aren't spelled out before checkout

Compounded drugs are not FDA-approved. Understand the medication options.

Check Nolu pricing Read the full Nolu review

Enhance MD

Shoppers who want flat pricing that doesn't rise with the dose, routine lab monitoring and a semaglutide-plus-tirzepatide combo option, and who don't need a brand-name or oral route.

Reasons to consider it

Every plan is priced on the homepage before any quiz: semaglutide $212, tirzepatide $280, a semaglutide-plus-tirzepatide combo $322 and microdosed tirzepatide $169
The monthly price stays the same as your dose goes up
Lab testing every six months and ongoing provider messaging are built into the price rather than sold separately

What to weigh up

Compounded only, with no brand-name Wegovy, Ozempic, Mounjaro or Zepbound
No oral or sublingual GLP-1, so every option is an injection
The $112 and $180 on the homepage are first-month prices; from month two you pay $212 and $280

Compounded drugs are not FDA-approved. Understand the medication options.

Check Enhance MD pricing Read the full Enhance MD review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

NoluEnhance MD

Normalized Cost/Month: Nolu:
73/100; Enhance MD:
65/100

Price Transparency: Nolu:
94/100; Enhance MD:
88/100

Nationwide Access: Nolu:
90/100; Enhance MD:
66/100

Formulation Options: Nolu:
78/100; Enhance MD:
74/100

Clinical Oversight: Nolu:
55/100; Enhance MD:
85/100

Contract Flexibility: Nolu:
78/100; Enhance MD:
82/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.