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Head-to-head · Cost-Efficiency Index

Mirabel Meds vs Ryze Rx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #360

Mirabel Meds

Shoppers drawn to a premium-positioned brand who don't mind requesting pricing directly.

Visit Mirabel Meds
VS
Grade C · #364

Ryze Rx

Cost-first shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.

Visit Ryze Rx

The verdict

Too close to callGrade C vs C

Mirabel Meds and Ryze Rx tie on the Cost-Efficiency Index at 54/100, so neither wins outright on the numbers. For most shoppers we'd start with Mirabel Meds (ranked #360, a hair above #364) — Shoppers drawn to a premium-positioned brand who don't mind requesting pricing directly. But Ryze Rx is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Mirabel Meds.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
43

Price Transparency

20
78

Nationwide Access

86
24

Formulation Options

53
66

Clinical Oversight

80
75

Contract Flexibility

55
41

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecMirabel MedsRyze Rx
Cost-Efficiency Index54/10054/100
Semaglutide / moNot disclosed$199/mo (starting dose, 3 month plan, compounded)
Tirzepatide / moNot disclosed$199/mo (starting dose, 3 month plan, compounded)
Semaglutide / yr (modeled)$2,388
Tirzepatide / yr (modeled)$2,388
CoverageAll 50 statesCoverage not published
Oral / sublingualNoNo
Brand-name accessYesCompounded only
Rank here#360#364

Mirabel Meds

54/100

Where the value is

  • Claims LegitScript certification with a visible badge
  • Nationwide coverage across all 50 states
  • Offers a microdose GLP-1 tier alongside standard semaglutide/tirzepatide

The tradeoffs

  • The originally-known domain (mirabelmeds.com) is a dead/expired deployment
  • Zero pricing disclosed anywhere on the site
Visit Mirabel Meds

Full Mirabel Meds review →

Ryze Rx

54/100

Where the value is

  • Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
  • Physician consultation, ongoing clinical support and discreet shipping included with each prescription
  • Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)

The tradeoffs

  • Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
  • Pharmacy partners not named - only 'US-licensed compounding pharmacies'
Visit Ryze Rx

Full Ryze Rx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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