Head-to-head · Cost-Efficiency Index
Metabolyz vs T2D.com
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Metabolyz
Patients comfortable committing to a consultation before knowing any price.
Visit MetabolyzT2D.com
Shoppers who already have a semaglutide prescription from an outside provider and just want a cheap fill-and-ship pharmacy.
Visit T2D.comThe verdict
Metabolyz and T2D.com tie on the Cost-Efficiency Index at 53/100, so neither wins outright on the numbers. For most shoppers we'd start with Metabolyz (ranked #375, a hair above #382) — Patients comfortable committing to a consultation before knowing any price. But T2D.com is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Metabolyz.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Metabolyz | T2D.com |
|---|---|---|
| Cost-Efficiency Index | 53/100 | 53/100 |
| Semaglutide / mo | Not disclosed | $99/mo (0.25 mg dose, compounded) |
| Tirzepatide / mo | Not disclosed | Not disclosed |
| Semaglutide / yr (modeled) | — | $1,188 |
| Tirzepatide / yr (modeled) | — | — |
| Coverage | All 50 states | 1 state |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #375 | #382 |
Metabolyz
53/100Where the value is
- Offers all three common GLP-1 tiers: semaglutide, tirzepatide, and a microdose option
- Nationwide coverage across all 50 states
- Includes coaching (nutrition, movement, lifestyle) bundled with the medical program
The tradeoffs
- Zero public pricing -- the site explicitly refuses to publish rates, a transparency red flag
- No named medical director or compounding pharmacy partner
T2D.com
53/100Where the value is
- $170/mo all-inclusive full-service price (prescriber + medication) is meaningfully below many compounded-GLP-1 competitors
- $99/mo BYOP option is a genuine discount for patients who already hold a valid outside prescription
- No-contract, cancel-anytime billing stated explicitly on the pricing page
The tradeoffs
- No published tirzepatide price anywhere on the site despite tirzepatide being advertised — pricing parity with semaglutide is assumed, not confirmed
- State availability is not disclosed anywhere on the public site — impossible to confirm eligibility pre-signup
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.