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Head-to-head · Cost-Efficiency Index

CoreAge Rx vs Metabolyz

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A · #1

CoreAge Rx

Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.

Visit CoreAge Rx
VS
Grade C · #375

Metabolyz

Patients comfortable committing to a consultation before knowing any price.

Visit Metabolyz

The verdict

Winner · CoreAge RxGrade A vs C

CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 53. Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. Metabolyz still earns a CPatients comfortable committing to a consultation before knowing any price.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

93
45

Price Transparency

97
20

Nationwide Access

98
86

Formulation Options

84
40

Clinical Oversight

90
82

Contract Flexibility

95
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCoreAge RxMetabolyz
Cost-Efficiency Index94/10053/100
Semaglutide / mo$99/moNot disclosed
Tirzepatide / mo$149/moNot disclosed
Semaglutide / yr (modeled)$1,188
Tirzepatide / yr (modeled)$1,788
CoverageAll 50 statesAll 50 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank here#1#375

CoreAge Rx

94/100

Where the value is

  • Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
  • Both compounded semaglutide and tirzepatide on one account at published prices
  • Available in all 50 states — no coverage gamble

The tradeoffs

  • Not the rock-bottom sticker price — 30 of the 381 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
  • No FDA-approved brand-name option (compounded only)
Visit CoreAge Rx

Full CoreAge Rx review →

Metabolyz

53/100

Where the value is

  • Offers all three common GLP-1 tiers: semaglutide, tirzepatide, and a microdose option
  • Nationwide coverage across all 50 states
  • Includes coaching (nutrition, movement, lifestyle) bundled with the medical program

The tradeoffs

  • Zero public pricing -- the site explicitly refuses to publish rates, a transparency red flag
  • No named medical director or compounding pharmacy partner
Visit Metabolyz

Full Metabolyz review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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