Head-to-head · Cost-Efficiency Index
Medsol RX vs Zenbody
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Medsol RX
Shoppers who will actually commit to a 12-month prepay and want the lowest possible locked-in monthly rate.
Visit Medsol RXZenbody
Shoppers who want the choice of a weekly injection or a daily oral tablet for either semaglutide or tirzepatide, and who will confirm the month-two price before paying.
Visit ZenbodyThe verdict
Medsol RX and Zenbody tie on the Cost-Efficiency Index at 65/100, so neither wins outright on the numbers, so choose on fit. Medsol RX: Shoppers who will actually commit to a 12-month prepay and want the lowest possible locked-in monthly rate. Zenbody: Shoppers who want the choice of a weekly injection or a daily oral tablet for either semaglutide or tirzepatide, and who will confirm the month-two price before paying.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Medsol RX.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Medsol RX | Zenbody |
|---|---|---|
| Cost-Efficiency Index | 65/100 | 65/100 |
| Semaglutide / mo | $199/moCompounded | $149/moStarting-dose intro price for the injection, compounded; oral tablet from $199 |
| Tirzepatide / mo | $259/moCompounded | $179/moStarting-dose intro price for the injection, compounded; oral tablet from $299 |
| Semaglutide / yr (modeled) | $2,388 | $1,788 |
| Tirzepatide / yr (modeled) | $3,108 | $2,148 |
| Coverage | All 50 states | Not published |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #204 | #210 |
Medsol RX
65/100Where the value is
- Every commitment tier bundles a dedicated care coach, custom treatment plan, and medical oversight at no extra charge
- Genuine month-to-month option exists with no long-term lock-in, unlike some peers that require prepay
- HSA/FSA eligible with Klarna financing offered
The tradeoffs
- The eye-catching $129/$199 headline prices require a full 12-month prepay ($1,548-$2,388 charged upfront) — the flexible month-to-month rate is $199/$259, notably higher
- No compounding pharmacy is named — only a generic 'certified U.S. pharmacies' claim
Zenbody
65/100Where the value is
- Both semaglutide and tirzepatide come as a weekly injection or a daily oral tablet, with each format priced on its product page
- The monthly price includes the medication, clinical oversight, dose adjustments, care-team messaging and shipping, with no insurance needed
- You can pause or cancel at any time, and a cancellation keeps your access through the end of the billing period
The tradeoffs
- The advertised prices are introductory starting-dose figures; the site says flat monthly pricing applies after the first month but doesn't print that price, so check it at checkout
- The homepage also advertises 40% off your first month without saying which figure the discount applies to
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.