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Head-to-head · Cost-Efficiency Index

CoreAge Rx vs Medsol RX

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A · #1

CoreAge Rx

Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.

Visit CoreAge Rx
VS
Grade C · #134

Medsol RX

Shoppers who want flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach.

Visit Medsol RX

The verdict

Winner · CoreAge RxGrade A vs C

CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 67. Best value on the board: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. Medsol RX still earns a CShoppers who want flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

93
47

Price Transparency

97
78

Nationwide Access

98
86

Formulation Options

84
66

Clinical Oversight

90
80

Contract Flexibility

95
41

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCoreAge RxMedsol RX
Cost-Efficiency Index94/10067/100
Semaglutide / mo$149/mo$209/mo (compounded)
Tirzepatide / mo$349/mo$250/mo (compounded)
Semaglutide / yr (modeled)$1,788$2,508
Tirzepatide / yr (modeled)$4,188$3,000
CoverageAll 50 statesAll 50 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank on the board#1#134

CoreAge Rx

94/100

Where the value is

  • Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
  • Both compounded semaglutide and tirzepatide on one account at published prices
  • Available in all 50 states — no coverage gamble

The tradeoffs

  • Not the rock-bottom sticker price — cheaper teaser tiers exist (Direct GLP lists $65, Ondra $93 on semaglutide)
  • No FDA-approved brand-name option (compounded only)
Visit CoreAge Rx

Full CoreAge Rx review →

Medsol RX

67/100

Where the value is

  • Compounded semaglutide from $209/mo (12-mo plan) and tirzepatide from ~$250/mo; HSA/FSA eligible with Klarna financing
  • Every plan bundles the medication, a dedicated care coach, custom treatment plan, medical oversight, and free shipping
  • Board-certified clinicians via OpenLoop; same-day approvals; ships nationwide

The tradeoffs

  • Doesn't name its compounding pharmacy (generic 'certified U.S. pharmacies')
  • No legal entity name published on the site
Visit Medsol RX

Full Medsol RX review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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