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WeighLab

MD Trim Clinic vs Defy Medical

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

MD Trim Clinic

Provider comparison

Patients near Phoenix, AZ or Novato, CA who want an in-person option and don't mind discovering price only after booking.

Semaglutide / month
Not disclosed
Tirzepatide / month
Not disclosed
Index 44/100 · Grade CChecked August 2026
Check MD Trim Clinic pricing Read review

Defy Medical

Provider comparison

Men already in TRT or hormone care who want to add a GLP-1 with the same clinic, rather than shoppers comparing GLP-1 prices alone.

Semaglutide / month
Not disclosed
Tirzepatide / month
Not disclosed
Index 43/100 · Grade CChecked August 2026
Check Defy Medical pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

MD Trim Clinic has the higher Cost-Efficiency Index: 44/100 versus 43/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

MD Trim Clinic
2 states
Defy Medical
Coverage not published

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

MD Trim Clinic

Defy Medical

Semaglutide / month
MD Trim Clinic: Not disclosed
Defy Medical: Not disclosed
Tirzepatide / month
MD Trim Clinic: Not disclosed
Defy Medical: Not disclosed
Semaglutide / year (modeled)
MD Trim Clinic: —
Defy Medical: —
Tirzepatide / year (modeled)
MD Trim Clinic: —
Defy Medical: —
State availability
MD Trim Clinic: 2 states
Defy Medical: Coverage not published
Oral / sublingual option listed
MD Trim Clinic: Not listed
Defy Medical: Yes
Brand-name access listed
MD Trim Clinic: Not confirmed
Defy Medical: Not confirmed
Provider facts checked
MD Trim Clinic: August 2026
Defy Medical: August 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

MD Trim Clinic

Patients near Phoenix, AZ or Novato, CA who want an in-person option and don't mind discovering price only after booking.

Reasons to consider it

  • Named medical director (Dr. Brandon Shaw, D.O.) rather than anonymous clinical leadership
  • Offers a genuine in-person option in two markets, not telehealth-only
  • Says its medications come from a LegitScript-certified pharmacy

What to weigh up

  • Zero dollar pricing published on its site
  • Specific compounding pharmacy is not named, only described as 'a third-party pharmacy'
  • We didn't see a LegitScript seal on the site; ask the clinic which pharmacy fills your prescription
Check MD Trim Clinic pricing Read the full MD Trim Clinic review

Defy Medical

Men already in TRT or hormone care who want to add a GLP-1 with the same clinic, rather than shoppers comparing GLP-1 prices alone.

Reasons to consider it

  • Named, credentialed Medical Director (Dr. Justin Saya)
  • Large third-party review base (3,999 Trustpilot reviews, 5-star average)
  • Offers both semaglutide and tirzepatide alongside broader men's-health services

What to weigh up

  • GLP-1 is clearly a secondary offering bolted onto a primarily TRT/hormone-optimization practice, not its core focus
  • Zero pricing disclosed on its site -- fully gated behind quiz/consultation
  • No LegitScript certification
Check Defy Medical pricing Read the full Defy Medical review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

MD Trim ClinicDefy Medical
Normalized Cost/Month
MD Trim Clinic:
45/100
Defy Medical:
45/100
Price Transparency
MD Trim Clinic:
20/100
Defy Medical:
20/100
Nationwide Access
MD Trim Clinic:
42/100
Defy Medical:
24/100
Formulation Options
MD Trim Clinic:
40/100
Defy Medical:
56/100
Clinical Oversight
MD Trim Clinic:
80/100
Defy Medical:
80/100
Contract Flexibility
MD Trim Clinic:
55/100
Defy Medical:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.