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Head-to-head · Cost-Efficiency Index

LunaRx vs Wisp

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #197

LunaRx

Shoppers who value simple flat-rate pricing and a no-cost-if-declined guarantee over named clinical credentials.

Visit LunaRx
VS
Grade C · #202

Wisp

Cost-first shoppers who want branded injectables plus a sublingual semaglutide alternative.

Visit Wisp

The verdict

Too close to callGrade C vs C

LunaRx and Wisp tie on the Cost-Efficiency Index at 63/100, so neither wins outright on the numbers. For most shoppers we'd start with LunaRx (ranked #197, a hair above #202) — Shoppers who value simple flat-rate pricing and a no-cost-if-declined guarantee over named clinical credentials. But Wisp is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs LunaRx.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

70
58

Price Transparency

78
86

Nationwide Access

24
24

Formulation Options

66
77

Clinical Oversight

83
82

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecLunaRxWisp
Cost-Efficiency Index63/10063/100
Semaglutide / mo$149/mo (compounded)$225/mo (compounded oral)
Tirzepatide / mo$199/mo (compounded)Not disclosed
Semaglutide / yr (modeled)$1,788$2,700
Tirzepatide / yr (modeled)$2,388
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoYes
Brand-name accessCompounded onlyYes
Rank here#197#202

LunaRx

63/100

Where the value is

  • Advertises simple, flat-rate pricing with no hidden fees
  • '$0 if not approved' removes financial risk from a declined consult
  • Founder is publicly named (Anamaria Galvan, RN) rather than fully anonymous leadership

The tradeoffs

  • No named physician medical director -- only an RN founder is identified
  • No named compounding pharmacy partner
Visit LunaRx

Full LunaRx review →

Wisp

63/100

Where the value is

  • Broad GLP-1 menu — branded injectables (Wegovy, Zepbound, Saxenda) plus a compounded sublingual option
  • LegitScript certified with named board-certified providers (Dr. Shannon Chatham DO, Andrea Sleeth WHNP-BC)
  • Unusually candid about the sublingual option's limits, noting effectiveness in patients may vary

The tradeoffs

  • The $99/mo tirzepatide figure is a consultation-and-care subscription, not the medication: Zepbound is filled at a pharmacy of your choice at its own cost, which Wisp does not publish
  • The compounded semaglutide option is sublingual drops, which Wisp itself describes as less effective than injection
Visit Wisp

Full Wisp review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

Keep comparing

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