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Head-to-head · Cost-Efficiency Index

LillyDirect Foundayo vs MEDGm

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #186

LillyDirect Foundayo

Patients who want an FDA-approved, manufacturer-direct oral GLP-1 rather than a compounded injectable.

Visit LillyDirect Foundayo
VS
Grade C · #193

MEDGm

Readers who want the dispensing pharmacies and the prescribing practices named, and who will price the second month rather than the first.

Visit MEDGm

The verdict

Winner · LillyDirect FoundayoGrade C vs C

LillyDirect Foundayo takes it, leading the Cost-Efficiency Index 63 to 60. Foundayo is Eli Lilly's own first-party, FDA-approved oral GLP-1 (orforglipron). MEDGm still earns a CReaders who want the dispensing pharmacies and the prescribing practices named, and who will price the second month rather than the first.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs LillyDirect Foundayo.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
41

Price Transparency

54
36

Nationwide Access

86
86

Formulation Options

69
77

Clinical Oversight

76
73

Contract Flexibility

55
67

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecLillyDirect FoundayoMEDGm
Cost-Efficiency Index63/10060/100
Semaglutide / moNot disclosed$299/mo month-to-month (the advertised $179 is the first month only, after an automatically applied coupon)
Tirzepatide / moNot disclosed$399/mo month-to-month (the advertised $279 is the first month only)
Semaglutide / yr (modeled)$3,588
Tirzepatide / yr (modeled)$4,788
CoverageAll 50 statesAll 50 states
Oral / sublingualYesYes
Brand-name accessYesCompounded only
Rank here#186#193

LillyDirect Foundayo

63/100

Where the value is

  • First-party Eli Lilly program -- highest possible manufacturer authenticity
  • FDA-approved branded drug (orforglipron), not an unapproved compounded formulation
  • Published self-pay starting price ($149) via savings card

The tradeoffs

  • Not semaglutide or tirzepatide -- a different molecule (orforglipron), so not directly comparable on this list
  • The $149 price is tied to a specific Savings Card program with its own terms, not an unconditional list price
Visit LillyDirect Foundayo

Full LillyDirect Foundayo review →

MEDGm

60/100

Where the value is

  • Names all four pharmacy partners in its terms, with street addresses, phone numbers and websites, and says which compounding classes they operate under
  • Names seven prescribing professional corporations on its consent page rather than referring to an unnamed medical group
  • Publishes the full ladder for three GLP-1 routes — injection, oral tablet and tirzepatide — at one, three, six and twelve months

The tradeoffs

  • "Starting at $179" is a first-month rate produced by an automatically applied coupon; the standing month-to-month price is $299, and the same shape applies to the oral tablet and to tirzepatide
  • The treatments FAQ says "your price never increases" on a plan whose price increases by $120 at the first renewal
Visit MEDGm

Full MEDGm review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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