Head-to-head · Cost-Efficiency Index
Layla vs Potere Health MD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Layla
Cost-first shoppers who want brand-name GLP-1 access from shoppers who don't need a compounded/lower-cost option.
Visit LaylaPotere Health MD
Cost-first shoppers who want low-cost, physician-led GLP-1 weight loss without a subscription.
Visit Potere Health MDThe verdict
Layla and Potere Health MD tie on the Cost-Efficiency Index at 59/100, so neither wins outright on the numbers. For most shoppers we'd start with Layla (ranked #274, a hair above #276) — Cost-first shoppers who want brand-name GLP-1 access from shoppers who don't need a compounded/lower-cost option. But Potere Health MD is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Layla.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Layla | Potere Health MD |
|---|---|---|
| Cost-Efficiency Index | 59/100 | 59/100 |
| Semaglutide / mo | $1,399/mo (brand Ozempic, promotional rate) | $80/mo (starting dose, compounded) |
| Tirzepatide / mo | $1,399/mo (brand Mounjaro, promotional rate) | $135/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $16,788 | $960 |
| Tirzepatide / yr (modeled) | $16,788 | $1,620 |
| Coverage | Coverage not published | 1 state |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #274 | #276 |
Layla
59/100Where the value is
- All-inclusive pricing bundles health check-ins, telehealth visits, prescription and unlimited doctor messaging into one price
- Named Medical Director (Dr. Ruth Cohen) disclosed on-site
- LegitScript-certified badge displayed; fast 2-3 day shipping claimed
The tradeoffs
- Brand-only and expensive: the real floor is $1,399/mo (Ozempic/Mounjaro), not the $1,299 the homepage FAQ separately claims — the two figures don't reconcile
- The lowest Zepbound figure shown ($1,599) is a one-time new-customer discount off a $1,699 standing price, not an ongoing rate
Potere Health MD
59/100Where the value is
- Low starting pricing (about $80-$135/month) with no subscription lock-in
- Physician-led by a named MD, not automated messaging
- Third-party COA and LegitScript-certified pharmacy
The tradeoffs
- Available in Utah only — a St George clinic offering telehealth within the state, not a national service
- The per-vial price is fixed, so the monthly cost rises steeply with the dose: the provider's own table runs about $20/mo at 0.25 mg, $80/mo at 1.0 mg and about $199/mo at 2.5 mg
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.